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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.

L-cystine and vitamin B6 at high doses prevented hair loss in mice treated with a chemotherapy drug.

Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.

Understanding skin structure and development helps diagnose and treat skin disorders.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

An imbalanced gut and lack of biotin can cause hair loss in mice.

The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

The conclusion is that managing cholesterol is important for women, especially during pregnancy, breastfeeding, and with PCOS, and involves regular screening and careful treatment choices.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Adult hair follicle cells can create new hair follicles from corneal cells with the right support.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.

Wound healing insights can improve regenerative medicine.

Recombinant human growth hormone helps burn wounds heal faster by increasing blood vessel growth.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.