January 2011 in “Guangdong Medical Journal” This study observed that Vitamin D receptor expression at protein and mRNA levels was significantly lower in the hair follicles of alopecia areata patients compared to healthy individuals.
October 2022 in “The American journal of gastroenterology” This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the mutant hairless rhino bald protein in mice interacts with the vitamin D receptor but cannot repress its transactivation and shows abnormal cellular localization.
May 2016 in “Research opinions in animal & veterinary sciences” In this study, aspartame consumption during gestation in rats was associated with significant histological changes and increased apoptosis in the skin of their neonatal pups.
149 citations
,
December 2007 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.
34 citations
,
June 1992 in “Journal of Cutaneous Pathology” In this case study, electron microscopy revealed that harlequin ichthyosis involves giant mitochondria in keratinocytes and abnormal lamellar granule development, which may contribute to pathogenesis through altered lipid metabolism.
11 citations
,
November 1998 in “Journal of dermatological science” This review summarizes studies on knockout mouse models revealing abnormalities in skin and hair follicle development but reports no new experimental results; the authors highlight the utility of these models for understanding hereditary skin disorders.
9 citations
,
November 1991 in “American Journal of Kidney Diseases” 6 citations
,
March 2010 in “Journal of plastic, reconstructive & aesthetic surgery” This article reviews the evolution of syndactyly repair techniques, highlighting a shift towards graftless approaches to avoid complications associated with skin grafts, but reports no new clinical outcomes.
6 citations
,
July 1994 in “Journal of Dermatological Science” This study found that introducing the recombinant rat OTC gene into SPF-ASH mice restored normal hair growth and metabolic function, improving symptoms associated with OTC deficiency.
3 citations
,
February 1992 in “Journal of veterinary medicine. Series A” This study found that an adult female farm-raised blue fox exhibited an abnormal hair growth cycle and seasonal estradiol variation, with a delayed winter coat cycle resulting in spring shedding.
1 citations
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April 2022 in “Journal of cosmetic dermatology” This study found that Krox20 is overexpressed in scar fibroblasts and may play a role in scar formation by upregulating genes involved in tissue remodeling and wound healing.
March 2012 in “Journal of Pediatric and Adolescent Gynecology” This study found that while most adolescents with PCOS do not show overt diabetes, over half have insulin resistance, and ethnicity is a significant predictor of type 2 diabetes.
June 2003 in “Plastic and Reconstructive Surgery” People with facial disfigurements are judged more negatively, highlighting the social benefits of corrective surgery.
June 2003 in “Obstetrical & Gynecological Survey” In this study, the size of vaginal prolapse was significantly linked to preoperative vaginal length and the length of vaginal excision following the Michigan four-wall sacrospinous suspension.
March 1990 in “Journal of Dermatological Science”
34 citations
,
December 2009 in “The International Journal of Developmental Biology” In this study, thymosin beta4 over-expression in transgenic mice was linked to accelerated hair growth and abnormal tooth development, suggesting roles in hair and tooth physiology.
21 citations
,
June 2009 in “Mammalian genome” This study describes a mouse model for Marie Unna Hereditary Hypotrichosis, identifying mutations in the hairless gene that result in sparse or absent hair and cyst-like hair follicles.
15 citations
,
August 1991 in “American Journal of Medical Genetics” This study observed that a low-protein, arginine-supplemented diet improved the abnormal hair appearance in untreated patients with argininosuccinic aciduria.
14 citations
,
August 1943 in “Archives of Dermatology” This study reported that applying natural or artificial folliculoid compounds to mouse skin caused estrous-like changes in internal sex organs, but did not lead to cancerous skin changes.
13 citations
,
April 1964 in “PubMed” This study found no significant differences in phosphatide distribution between normal and cancerous mouse epidermis during different stages of growth, despite variations in total phosphatide levels.
2 citations
,
August 2022 in “Reproductive Biology and Endocrinology” This study found that magnesium supplementation significantly improved overall quality of life in women with polycystic ovary syndrome, but did not significantly affect acne, alopecia, or abnormal uterine bleeding.
2 citations
,
December 2013 in “Veterinary dermatology” This study describes three adult dogs with sebaceous gland dysplasia, reporting that two showed moderate to marked improvement in symptoms with treatment, though ongoing management is required as the condition cannot be cured.
This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.
February 2025 in “Journal of Investigative Dermatology” The ZIP13 variant is linked to abnormal hair quality.
March 2014 in “Journal of The American Academy of Dermatology” Vitamin D deficiency is common in temporary hair loss, and stress is often a suspected cause.
578 citations
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April 1993 in “Cell” This study found that mice with a disrupted TGFα gene display a curly whisker-coat phenotype, similar to waved-1 mice, suggesting TGFα's crucial role in skin architecture and hair development.
139 citations
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December 2021 in “Journal of Clinical Medicine” This systematic review reports that fatigue was the most common symptom in both phases of long COVID, with lung function issues more frequent in the ongoing symptomatic phase and psychological burdens like anxiety and depression more prevalent in the post-COVID syndrome phase.
33 citations
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April 2003 in “Oncogene”
32 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This systematic review found that long COVID symptoms, particularly fatigue, sleep disorder, and dyspnoea, were similarly prevalent in ongoing symptomatic COVID-19 and post-COVID-19 syndrome, but psychological issues and poor quality of life were more common in the latter.