6 citations,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
5 citations,
January 2021 in “Biomedicine & Pharmacotherapy” Policosanol helps treat hair loss by balancing hormones and supporting hair growth.
2 citations,
May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
July 2014 in “Acupuncture & electro-therapeutics research” Visible and invisible changes on the face and hands can indicate heart problems, and manual hand stimulation can relieve chest pain.
26 citations,
September 1969 in “The American journal of medicine” Cronkhite-Canada Syndrome often leads to death within 6-18 months.
15 citations,
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
April 2024 in “International journal of molecular sciences” Dermal factors are crucial in regulating melanin production in skin.
68 citations,
November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
29 citations,
September 1989 in “Journal of The American Academy of Dermatology” Abnormal scalp whorls can indicate brain development issues but may also be seen in neurologically normal people.
18 citations,
July 2019 in “Clinical Endocrinology” Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.
17 citations,
July 2014 in “Journal of Ultrasound in Medicine” Abnormal cuticle and hair shaft medulla cause hair loss in androgenetic alopecia; sonography helps diagnose and manage it.
1 citations,
October 2020 in “Research Square (Research Square)” Abnormal Wnt signaling in hair follicle stem cells can lead to acne-like cysts.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Abnormal contraction of connective tissue in hair follicles causes hair loss by killing off important cells, and treating this could improve hair growth.
August 2022 in “International journal of reproduction, contraception, obstetrics and gynecology” The study found that 7.21% of young girls have polycystic ovarian syndrome, with symptoms like irregular periods, abnormal hair growth, and acne. Early diagnosis is important to prevent long-term complications.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The early genes of a specific virus can cause abnormal skin cell growth and hair follicle changes.
July 2019 in “International journal of contemporary medical research” Men with genetic hair loss are more likely to have abnormal blood lipid levels, especially if the hair loss is severe.
96 citations,
December 2002 in “Experimental dermatology” NGAL indicates abnormal skin cell differentiation.
19 citations,
March 1988 in “International Journal of Dermatology” Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.
14 citations,
September 2015 in “Ophthalmic plastic and reconstructive surgery” Surgical removal of abnormal fat pads fixed the woman's eyelid issue caused by likely silicone injections.
11 citations,
January 2015 in “Journal of cellular physiology” HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.
6 citations,
May 1987 in “Acta dermato-venereologica” Syphilis patients showed abnormal hair root changes, with no difference between primary and secondary stages.
3 citations,
January 1994 in “Toxicological Sciences” Finasteride causes abnormal growth in male mice cells at high doses.
2 citations,
August 2022 in “Emergency medicine international” Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.
1 citations,
January 2002 in “Dermatology + psychosomatics” Most people worried about abnormal hair loss actually have psychological issues like depression or anxiety.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
May 2022 in “Experimental dermatology” Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
December 2021 in “Molecular genetics and genomics” Cats with abnormal hair had DSG4 gene changes causing hair problems.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebaceous gland atrophy and abnormal function may contribute to hair loss in psoriasis.
35 citations,
September 2006 in “American Journal Of Pathology” Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.
32 citations,
April 2015 in “British Journal of Dermatology” The hair shedding scale accurately identifies abnormal hair shedding in women with long hair, with grades 5 and 6 indicating excessive shedding.