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The zinc finger protein 3 in Arabidopsis thaliana reduces plant growth and root hair development.

This study reported that UVR induced PKCε phosphorylation of Stat3 in transgenic mice, suggesting a role in enhancing sensitivity to UVR-related skin cancer development.

This review discusses the roles of hypoxia and epigenetics in cellular reprogramming and their contributions to tissue regeneration, reporting no new experimental results.

This review examines the role of Sonic Hedgehog signaling in the maintenance and repair of skin and lung barriers, and its influence on inflammation and atopic diseases; it presents no new clinical findings.

This review discusses how targeting protein degradation processes may help overcome cancer drug resistance, but reports no new clinical results and suggests further research for precise therapeutic strategies.

This review highlights that alopecia areata, a common type of hair loss, currently lacks preventive or curative treatments, and traditional therapies such as minoxidil and corticosteroids offer inconsistent results, necessitating patient-consensual treatment planning.

This study found that LSD1 is crucial for embryonic skin barrier formation in mice, revealing its significant role in epidermal development and suggesting its potential as a target in skin diseases with barrier defects.

This review discusses the hedgehog signaling pathway's role in cutaneous tumors and hematological disorders, highlighting its potential as a therapeutic target, but reports no new clinical findings.

In this study, mouse models with EGFR deficiency showed that disrupted hair follicle cycling leads to increased mast cell numbers and inflammation, suggesting EGFR's role in managing hair cycle transitions and preventing folliculitis.

This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.

This study found that CXCL12+ fibroblast subsets in mouse skin play a critical role in recruiting neutrophils and defending against S. aureus infection, with similar fibroblast activity observed in human psoriatic skin.

This article reviews the molecular events in legume-rhizobia symbiosis, focusing on gene regulation, symbiotic pathways, and infection processes, but does not present new experimental findings.

In this study, deleting the gene Mettl3 in mouse epidermal progenitors resulted in impaired epithelial development and self-renewal, highlighting m⁶A's crucial role in regulating chromatin modifiers and maintaining normal epithelial tissue function.

In this study, researchers found that the SLICK1 allele in cattle may alter local immune regulation, hair growth, and tissue remodeling, as indicated by differential gene expression pathways associated with immune and inflammatory responses in slick vs. nonslick Holsteins.

This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.

This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.

This review focuses on S100A6, a Ca²⁺-binding protein, detailing its role in cell functions, the regulation of its expression, and its potential as a biomarker and therapeutic target in various diseases.

This review discusses potential therapeutic options for frontal fibrosing alopecia by exploring distinct signaling pathways and cellular players, but reports no new clinical findings and emphasizes the need for further trials.

This review examined the pathological effects of mechanical pressure on human skin at the cellular level, highlighting how various skin cell types respond to pressure, potentially leading to pathological changes such as inflammation, ischemia, and impaired differentiation.

In this study, baicalin from Scutellaria baicalensis decreased androgen levels in both cells and PCOS model rats by inhibiting key gene expression, suggesting it may be a potential treatment for hyperandrogenism in PCOS.

This review examines the complex mechanisms that regulate skin stem cell development, activation, and differentiation, emphasizing the molecular signaling pathways that influence their fate and contribute to skin homeostasis.

This study demonstrated that Wnt5a can serve as an orienting signal for mouse skin's planar cell polarity but its overexpression disrupts hair follicle orientation, which can be rescued by modifying Fzd6 levels.

This review discusses the molecular mechanisms driving hair follicle degeneration in skin aging and emphasizes the role of the tissue microenvironment on stem cell function, but reports no new research findings.

This study used single-cell techniques and lineage tracing to reveal that integrin α6 expression in neural crest cells can differentiate them into Schwann cells, melanocytes, and fibroblasts in skin, identifying integrin α6 as a potential marker for these derivatives.

In this study, miR-221 was identified as a key factor in androgenetic alopecia pathogenesis due to its role in suppressing hair growth by interacting with androgen receptors and affecting related pathways.

This study used developing mouse hair follicles to explore early epithelial bud formation, finding that the Rho GTPase regulator ARHGEF3 plays a crucial role in regulating cell fate and cadherin patterning, with knockouts showing disrupted morphology and increased straight hair follicle growth.

This study found that inhibiting the HEDGEHOG-GLI1 pathway could reduce keloid size and gene expression, suggesting it as a potential therapeutic target for keloid pathogenesis.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

This review discusses common hair loss conditions and explores how advancements in hair follicle biology might lead to more effective treatments but reports no new results.

This article reviews the genetic mutations associated with hypohidrotic ectodermal dysplasia and reports no new clinical results; the authors highlight the roles of EDA gene isoforms and related receptors.