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Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Women with PCOS have lower quality of life, especially in mental health and energy, and managing weight can help improve it.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Fat cells in the skin help start healing and form important repair cells after injury.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.