11 citations
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May 2018 in “Frontiers in plant science” This study found that overexpressing the PCaP2 protein in Arabidopsis enhanced drought tolerance by influencing ABA and SA signaling pathways and regulating root hair growth, suggesting a key role in water deficit response.
1 citations
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April 2017 in “Journal of Investigative Dermatology” Abatacept may help some people with alopecia areata regrow hair.
August 2025 in “BMC Women s Health” This study found significant gaps in the knowledge, attitude, and practices of healthcare professionals in Ethiopia regarding the diagnosis of PCOS, with many relying only on ultrasonography and physical symptoms, underscoring the need for better diagnostic channels and education efforts.
January 2024 in “Editora In Vivo eBooks” This case report documents a dog with dermatophytosis, caused by the fungus Microsporum canis, presenting symptoms like alopecia in the neck and ear, highlighting the condition's prevalence in tropical and temperate climates and its zoonotic nature.
2 citations
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November 2022 in “Frontiers in Pharmacology” This study systematically documented the ethnobotanical and ethnomedicinal knowledge from traditional healers in Addis Ababa, identifying 81 medicinal plants, including the endangered Echinops kebericho, used primarily for treating skin and general diseases.
324 citations
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July 2020 in “Applied Water Science” This study found high levels of toxic heavy metals in water sources of mining communities in Abakaliki, Nigeria, posing potential health risks including Parkinson's and Alzheimer's diseases.
August 2024 in “Plant Signaling & Behavior” This study found that overexpressing the gene OsPRX83 in rice plants enhanced osmotic and oxidative stress tolerance compared to wild-type and mutant rice, showing potential for engineering drought-resistant rice varieties through ABA-dependent pathways and ROS scavenging.
55 citations
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October 2015 in “Journal of Investigative Dermatology” Alopecia areata is linked to immune-related genes, suggesting JAK inhibitors as a potential treatment.
47 citations
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October 2014 in “Expert Opinion on Emerging Drugs” This review discusses emerging treatments and mechanisms for alopecia, highlighting potential therapies like janus kinase inhibitors and advances in stem-cell technology, but reports no new experimental results.
43 citations
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December 2017 in “BMC Plant Biology” This study found that strigolactone biosynthesis and signaling components in soybean may interact with other hormone pathways, influencing soybean development and nodulation.
42 citations
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August 2016 in “Nanomedicine” In this study, TyroSpheres were used to encapsulate adapalene, increasing its solubility and enhancing skin distribution while reducing irritancy compared to a commercial formulation, indicating promise for acne treatment in ex vivo and in vitro settings.
34 citations
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March 2020 in “BMC plant biology” This study found that cotreatment with graphene oxide and indole-3-acetic acid significantly inhibited root development in Brassica napus, with the inhibition increasing as indole-3-acetic acid concentration rose.
24 citations
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March 2022 in “Frontiers in plant science” This review discusses the roles of phytohormones like auxin and ethylene in regulating root hair growth and development in plants, but it reports no new experimental results.
17 citations
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July 2018 in “Environmental and Experimental Botany” The researchers reported that silencing the NtNCED3-2 gene in tobacco reduced ABA content and drought tolerance, inhibited root and leaf development, and decreased photosynthetic ability due to altered isoprenoid metabolism.
16 citations
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June 2017 in “Advances in Therapy” This review summarizes recent research on alopecia areata, highlighting advances in targeted therapies due to improved understanding of its immunopathogenesis, though it reports no new clinical results.
14 citations
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June 2013 in “Joint Bone Spine” This review discusses current anti-inflammatory treatment options for calcium pyrophosphate crystal deposition disease (CPPD) and highlights the lack of crystal-targeted therapies, emphasizing the need for more research to guide treatment.
9 citations
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December 2017 in “The Journal of Allergy and Clinical Immunology” This review discusses the evolution of alopecia areata treatments towards more targeted therapies and reports no new clinical results, emphasizing cooperation between clinicians and scientists in understanding the disease's pathophysiology.
6 citations
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August 2013 in “Joint Bone Spine” Tocilizumab treatment was associated with significant hair regrowth in one patient and temporary hair loss followed by regrowth in another.
5 citations
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October 2022 in “Frontiers in bioengineering and biotechnology” Ro stress hindered ginseng root growth and ginsenoside production, but increased certain hormones and affected gene regulation related to plant growth and stress responses.
2 citations
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March 2015 in “Expert opinion on orphan drugs” This review discusses recent advances in the treatment of alopecia areata, highlighting new potential therapies like JAK inhibitors and PRP, and reports no new clinical results.
1 citations
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May 2023 in “Prospects in Pharmaceutical Sciences” This study reviews current treatments for alopecia areata, highlighting that despite various options like corticosteroids and immunosuppressives, their limited efficacy and potential side effects are challenges, while targeting specific cytokines has shown promise except with TNF inhibitors, which may worsen the condition.
1 citations
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October 2017 JAK inhibitors are effective for hair regrowth in severe alopecia areata.
1 citations
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January 2013 in “International Journal of Trichology” The conference discussed various hair disorders and treatments, including the use of topical steroids, high doses of cetrizine, and hair grafting, as well as the psychological impact of hair loss.
March 2021 in “Research Square (Research Square)” This study found that overexpression of the SbbHLH85 gene in sweet sorghum increases root hair growth and Na+ absorption, but negatively affects salt tolerance.
This study found that lateral root formation in plants in response to L. bicolor volatiles involves complex signaling processes, potentially including unknown proteins, CRKs, and ABA pathways.
November 2025 in “Skin Appendage Disorders” This study reviewed evidence on biologic drugs targeting immune cells for alopecia areata, finding mixed results: some achieved case-level hair regrowth, but controlled trials often showed limited efficacy.
July 2023 in “IntechOpen eBooks” This review highlights that alopecia areata, a common type of hair loss, currently lacks preventive or curative treatments, and traditional therapies such as minoxidil and corticosteroids offer inconsistent results, necessitating patient-consensual treatment planning.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study used machine learning to identify molecular predictors of drug response in alopecia areata, suggesting a tool for predicting treatment efficacy based on gene signatures.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, distinct molecular mechanisms of action were identified for three drugs used in alopecia areata clinical trials, providing insights for precision medicine and treatment selection.
March 2010 in “Anti-inflammatory & anti-allergy agents in medicinal chemistry” This review details the adverse effects and drug interactions of biologic agents used in rheumatoid disease treatment, highlighting their significant side effect profile without reporting new clinical findings.