1 citations
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November 2024 in “Revista JRG de Estudos Acadêmicos” This review discusses available treatments for androgenetic alopecia and highlights that, although no definitive treatment exists, current options generally achieve high satisfaction rates.
March 2026 in “Editora Pasteur eBooks” This study reviews hair follicle physiology and common scalp diseases such as androgenetic alopecia, telogen effluvium, and alopecia areata, highlighting their pathophysiology and current treatment approaches, which may include topical, systemic, and adjunctive therapies.
January 2026 in “Revista Eletrônica Acervo Saúde” This study reported that among individuals with long COVID, hematologic disturbances such as inflammation-related anemia, characterized by high hepcidin levels and restricted iron use, were prevalent, contributing to reduced capacity, fatigue, and slow recovery, especially in men and those with severe acute COVID-19.
November 2025 in “Health Promotion Evidence” This study reviewed interventions for post-COVID-19 alopecia and concluded that integrated physiotherapeutic strategies, including photobiomodulation, micro-needling, electrotherapy, and scalp massage, can reduce hair loss and improve hair density, contributing positively to patient quality of life.
July 2025 in “Revista Eletrônica Acervo Científico” This integrative literature review found that hydroxychloroquine may stabilize inflammatory scarring autoimmune alopecias like frontal fibrosing alopecia, especially when combined with other therapies, while its effectiveness in non-scarring alopecias appears inconsistent and is limited to refractory cases.
February 2025 in “Revista Eletrônica Acervo Saúde” This integrative review found that triamcinolone hexacetonide remains the primary treatment for mild to moderate alopecia areata but noted its significant side effects with prolonged use, while emerging therapies like PRP and minoxidil offer promising alternative benefits with fewer risks.
November 2024 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” In this study, a literature review concluded that minoxidil is safe and effective for treating androgenetic alopecia, with few side effects, and highlighted the role of pharmacists in optimizing treatment by monitoring use and fostering adherence.
Low-dose oral minoxidil is effective and generally safe for treating hair loss in women.
February 2024 in “Recima21” This study explored the connections between Covid-19 and hair loss issues like telogen effluvium and alopecia areata, highlighting the virus's potential trigger effect and underscoring the importance of comprehensive post-Covid-19 treatment strategies that consider immune, psychological, and hair cycle factors.
February 2024 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.
November 2023 in “Open Repository of the University of Porto (University of Porto)” This summary of a pharmacy internship reports on expanding scientific knowledge through diverse activities, including exploring diabetes medications for obesity treatment and discussing the role of nutritional supplements in geriatrics.
August 2023 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” This systematic review found that anxiety disorders are significantly more prevalent among patients with various psychodermatoses compared to the general population.
This article discusses the organizational aspects of the II National Academic Congress of Dermatology in Brazil and reports no new research findings.
January 2019 in “Oncogen” This report suggests that for prostate cancer patients with cardiovascular disease, prescribing the GnRH antagonist degarelix may reduce cardiac events compared to using GnRH agonists, although prescribing should consider potential cardiac risks, particularly in patients with pre-existing conditions or older age.
This study found that the ethanolic extract of Guazuma ulmifolia, or mutamba, showed only intermediate levels of phenolic compounds and low antioxidant activity in laboratory tests, suggesting limited potential in alleviating oxidative stress conditions like cancer or cardiovascular diseases.
July 2014 in “Journal of the Portuguese Society of Dermatology and Venereology” This review covers current knowledge of tricoscopy's applications in diagnosing and monitoring scalp and hair disorders but presents no new clinical results.
6 citations
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January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This report details the case of an 11-year-old girl with APECED syndrome carrying a unique homozygous mutation in the AIRE gene, the first of its kind documented.
26 citations
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June 2018 in “The journal of immunology/The Journal of immunology” This study demonstrated that AIRE-deficient rats exhibit key symptoms of APECED, making them a relevant model for exploring potential treatments.
7 citations
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September 2024 in “The Journal of Dermatology” This study evaluated the effectiveness and safety of ritlecitinib in patients aged 12 or older with alopecia totalis or universalis, finding higher hair regrowth response rates compared to placebo at 24 weeks, with continued improvement and acceptable safety through 48 weeks.
24 citations
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February 2011 in “The American journal of pathology” This study found that AIRE, a usually nuclear protein, is expressed in the cytoplasm of human epidermal and follicular keratinocytes and associates with the intermediate filament protein cytokeratin 17, potentially impacting ectodermal abnormalities in APECED syndrome.
This study in a nine-year-old boy from Lebanon identified a gene mutation (c.1066dup p.(Arg356Profs*16)) associated with a rare inborn error of immunity, characterized by craniosynostosis, jaundice, and several other symptoms, expanding the known genotypic and phenotypic spectrum of this condition.
26 citations
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September 2009 in “Clinical genetics” This study identified four novel and one recurrent mutation in the AIRE gene among Arab families with APS1, suggesting these contribute to the disorder.
2 citations
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October 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Aire‒/‒ mice spontaneously developed persistent AA-like lesions, highlighting a potential role for AIRE in hair follicle biology and pathogenesis of alopecia areata.
86 citations
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December 2002 in “Tissue Antigens” In this study, researchers found that the AIRE G961C variant is a significant risk factor for severe alopecia areata and early-onset cases, particularly in patients with alopecia universalis.
April 2020 in “Journal of evolution of medical and dental sciences” This report reviews the clinical presentation and genetic aspects of a case of acrodermatitis enteropathica in a one-year-old child but provides no new clinical findings.
March 2026 in “Experimental Dermatology” This study developed an in vitro model using NTERT keratinocytes expressing AEC-related TP63 mutations, which replicated skin defects observed in AEC patients and offers a valuable tool for understanding the disorder and developing new treatments.
March 2026 in “JID Innovations” In a mouse model study, researchers found that mutations in Aire reduced alopecia areata frequency, while Notch4 mutations did not lead to the disease, likely due to proximity with a resistance gene.
June 2026 in “Archives of Dermatological Research” In this study, the rs4541843 G > A variant was found to be significantly associated with increased risk and severity of alopecia areata, as well as elevated expression of hsa-miR-182-5p, suggesting their potential as molecular markers for diagnosis and severity assessment.
April 2016 in “Journal of The American Academy of Dermatology” A child on life support experienced rapid hair loss due to severe illness affecting hair growth.
43 citations
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November 2009 in “Archives of dermatology” This study found that alefacept showed no significant improvement in treating severe alopecia areata compared to placebo over a 24-week period.