2 citations
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January 2024 in “Journal of Personalized Medicine” This study found that combining adipose-derived mesenchymal stem cells with platelet-rich plasma improved key healing markers in bowel anastomoses in rats with induced colitis, suggesting potential benefits for anastomosis recovery even in inflamed conditions.
30 citations
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April 2020 in “Stem Cell Research & Therapy” This study found that the PI3K-Akt signaling pathway is essential for regenerating new hair follicles when epidermal stem cells and skin-derived precursors are combined, suggesting potential therapeutic applications for hair regeneration.
24 citations
,
June 2019 in “Journal of Cosmetic Dermatology” This study found that microneedling improved hair density and thickness with minimal side effects in patients with androgenetic alopecia and telogen effluvium.
April 2026 in “International Journal of Molecular Sciences” This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.
14 citations
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July 2021 in “Biomedicines” This review discusses the roles of platelets in hemostasis and wound repair, the preparation methods for platelet concentrates, and their therapeutic applications in medicine and dentistry, reporting no new clinical results.
This review highlights that alopecia areata is influenced by genetic, autoimmune, and environmental factors, with emerging treatments like JAK-2 inhibitors showing promise for severe cases.
July 2023 in “University of Debrecen Electronic Archive (University of Debrecen)” This review suggests that novel treatment developments targeting the pathomechanics of alopecia areata, such as JAK inhibitors, show promise, although optimal treatment strategies are still under investigation.
This review discusses various treatment options for alopecia areata, focusing on manipulating the immune response around hair follicles, but reports no new clinical results.
November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study reported two cases of severe multifocal alopecia areata successfully treated with a combination of topical minoxidil and intralesional platelet-rich plasma, resulting in significant hair regrowth, though further controlled trials are needed to confirm these findings.
In this study, a 46-year-old patient with alopecia areata experienced successful hair regrowth and improved quality of life after three monthly applications of platelet-rich plasma, which the authors noted is a relatively effective, safe, and minimally invasive treatment option.
November 2022 in “Frontiers in Medicine” This review suggests that platelet-rich plasma may be a promising treatment for immune-mediated alopecias, including alopecia areata and primary cicatricial alopecias, but definitive recommendations are limited due to insufficient high-quality evidence.
February 2018 in “Medicine - Programa De Formación Médica Continuada Acreditado” This review discusses current and emerging treatments for androgenic alopecia, noting that minoxidil and finasteride are the only FDA-approved options, while other methods lack comparable evidence of efficacy.
15 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the potential use of platelet-rich plasma for treating alopecia areata but reports no new experimental findings, noting the need for standardized protocols and larger studies to evaluate its efficacy.
7 citations
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July 2019 in “International journal of research in dermatology” This study reported that intralesional triamcinolone acetonide was more effective than intralesional PRP for treating scalp alopecia areata, with minimal recurrence and side effects like atrophy and hypopigmentation.
3 citations
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May 2018 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that platelet-rich plasma treatment was effective and safe for promoting hair regrowth in mild cases of alopecia areata, with significant improvements in quality of life compared to placebo.
1 citations
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January 2023 in “PubMed” This systematic review and meta-analysis found limited, low-quality evidence suggesting that platelet-rich plasma injections may increase hair density in patients with androgenetic alopecia compared to saline, but results were inconclusive for alopecia areata.
February 2024 in “Sohag Medical Journal” This review discusses the challenges in treating alopecia areata and the potential psychological impact, noting that spontaneous hair regrowth often occurs and highlighting the consideration of psychotherapy alongside treatment options; it reports no new experimental results.
December 2023 in “International journal of research in dermatology” In this study, adding intralesional platelet rich plasma to topical mometasone proved more effective and showed earlier improvement in treating alopecia areata compared to using topical mometasone alone.
24 citations
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January 2021 in “Dermatologic Therapy” This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.
61 citations
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January 2015 in “Indian Journal of Plastic Surgery” This study found that platelet-rich plasma may have a role in treating chronic alopecia areata, but more long-term follow-up studies are needed to confirm its effectiveness and success rate.
12 citations
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December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses platelet-rich plasma and microneedling for alopecia areata, reporting promising small-scale findings but no new results, and suggests further trials to determine efficacy and specific disease subtype suitability.
1 citations
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November 2017 in “Journal of Investigative Dermatology” This review discusses the potential use of platelet-rich plasma and microneedling for alopecia areata and reports encouraging findings, but no new clinical results; future research is needed to validate these treatments.
14 citations
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September 2015 in “PubMed” This review discusses treatment strategies for alopecia areata and emphasizes the importance of primary care physicians recognizing and managing the condition, with referrals to dermatologists for more severe cases.
January 2024 in “Dermatology Review” This study found that combining platelet-rich plasma with 4% hydroquinone was more effective in reducing melasma symptoms than using hydroquinone alone.
5 citations
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June 2024 in “Archives of Dermatological Research” This study found that fractional Er:YAG laser combined with platelet-rich plasma resulted in greater skin repigmentation in patients with localized stable vitiligo compared to microneedling with platelet-rich plasma, with fewer side effects reported in the laser group.
June 2022 in “Biotechnological Research” This review discusses the potential of activated autologous platelet-rich plasma (aaPRP) for improving diabetic foot ulcer outcomes but reports no new clinical results, noting the need for further evidence.
4 citations
,
March 2023 in “Current Oncology” This study reviews current methods and emerging approaches to prevent and treat chemotherapy-induced hair loss, reporting that evidence-based research is needed to validate effective strategies, which could enhance cancer patients’ quality of life and treatment compliance.
15 citations
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July 2020 in “Applied Sciences” This study found that a single injection of Platelet Rich Stroma improved knee function and reduced pain and stiffness in patients with knee osteoarthritis over twelve months.
3 citations
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April 2023 in “Urology Herald” This review discusses the use of platelet-rich plasma in urology and emphasizes the need for further multicenter studies to explore its potential benefits.
45 citations
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May 2024 in “International Journal of Molecular Sciences” This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.