111 citations
,
August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
108 citations
,
March 2011 in “Archives of Dermatology” Corkscrew hair may be a new sign for quickly diagnosing scalp fungus in black children.
72 citations
,
June 2013 in “Journal of feline medicine and surgery” This review discusses the infection dermatophytosis in cats and reports no new results; it emphasizes the difficulty of eradicating the disease in shelters and catteries.
71 citations
,
December 2010 in “Preventive Veterinary Medicine” This study found that Microsporum canis was the most prevalent dermatophyte in dogs and cats in Western Turkey, with younger animals more frequently infected than older ones.
69 citations
,
January 2020 in “Veterinary World” This review examines factors influencing dermatophyte infection in companion animals, focusing on prevalence, clinical signs, pathogenesis, immune response, and the impact of cortisol and cytokines, but reports no new clinical results.
62 citations
,
June 2015 in “Sexually Transmitted Infections” This study identifies sexual activity as a significant potential transmission route for Trichophyton interdigitale, causing tinea genitalis among travelers to South East Asia.
52 citations
,
January 2004 in “Medical mycology” This study reported an increase in tinea capitis in Stockholm children, mainly caused by Trichophyton violaceum and associated with immigration from Africa and family spread.
51 citations
,
May 2008 in “Mycoses” This study found that terbinafine HCl nail solutions with or without DDAIP HCl significantly outperformed ciclopirox nail lacquer in treating guinea pig dermatophytosis, suggesting potential effectiveness for human nail infections.
48 citations
,
July 1992 in “International Journal of Dermatology” HIV can cause various nail and hair disorders, important for early diagnosis and treatment.
46 citations
,
January 2002 in “Paediatric drugs” This review discusses treatment options for tinea capitis in children and reports no new clinical results; the authors recommend newer antifungal agents in cases of griseofulvin treatment failure.
42 citations
,
September 2018 in “Journal of Fungi” This study highlights the challenges in treating Microsporum canis infections due to variable antifungal drug efficacy and potential resistance, emphasizing the need for standardized methods to assess drug susceptibility.
41 citations
,
September 2007 in “Pediatric emergency care” This review discusses the challenges in diagnosing tinea capitis and highlights the need for laboratory confirmation and systemic treatment due to the limited effectiveness of topical antifungals; no new clinical results are presented.
38 citations
,
July 2010 in “Clinical, cosmetic and investigational dermatology” This review discusses systemic antifungal treatments for tinea capitis in children, noting that newer agents like terbinafine and itraconazole require shorter courses than the traditional griseofulvin, but may be more costly.
37 citations
,
August 1991 in “International Journal of Dermatology” This study reported a predominance of adult patients, mostly women, with Trichophyton violaceum tinea capitis in southern Taiwan, noting a bimodal age distribution and questioning whether this represents a new trend.
36 citations
,
October 2016 in “Medical mycology” This study at Mbarara University of Science and Technology found that T. violaceum is the most common cause of tinea capitis in children in Western Uganda, and systemic therapy is preferred over topical treatments for effective management due to the nature of the infection.
36 citations
,
February 2004 in “International Journal of Dermatology” Different sports can cause specific skin conditions that need proper diagnosis and treatment.
35 citations
,
October 2019 in “Journal of pediatric health care” This article reviews the clinical presentations, pathophysiology, and treatment options for various skin conditions in children with skin of color and reports no new findings.
35 citations
,
November 1996 in “Journal of the American Academy of Dermatology” This study reports two HIV-infected men with a rare M. canis infection unresponsive to ketoconazole and terbinafine, where itraconazole was effective but prolonged treatment led to only one cure.
33 citations
,
December 2013 in “Journal of cutaneous pathology” A fungal infection can look like a different scalp condition in teens, leading to wrong treatment until proper tests are done.
32 citations
,
January 2014 in “Dermatology Research and Practice” This study found that trichoscopy can rapidly and noninvasively diagnose tinea capitis and alopecia areata in pediatric patients by identifying specific hair patterns associated with each condition.
32 citations
,
August 2003 in “Journal of the American Academy of Dermatology” This case report describes three adults with inflammatory tinea capitis mimicking bacterial infection, emphasizing the need to consider this diagnosis in similar cases; all were successfully treated with oral antifungal agents.
30 citations
,
January 2013 in “International Journal of Trichology” This study found that in Jordanian children, tinea capitis, alopecia areata, and telogen effluvium were the most common causes of hair loss, with nutritional deficiencies such as iron and zinc deficiency also noted as significant factors.
28 citations
,
October 2000 in “International Journal of Dermatology” This case report details a 37-year-old man who developed eosinophilic pustular dermatosis after previously resolving herpes zoster, with successful treatment using itraconazole and cycloproxolamine.
28 citations
,
January 2000 in “Medical Mycology” This article reviews the impact of natural fungal pathogens on laboratory animal research and reports no new results, calling attention to infection risks with dermatophytes, Candida, and pneumonia in immunocompromised rodents.
27 citations
,
April 2012 in “Pediatrics in review” This article reviews approaches to diagnosing and treating dermatophytosis and pityriasis versicolor, noting a significant change in the epidemiology of tinea capitis and highlighting the limitations of certain diagnostic techniques.
26 citations
,
January 1990 in “Mycoses” This study reviewed tinea capitis cases in children at a dermatology clinic from 1977-1988, finding Trichophyton violaceum as the most common pathogen, with Moroccan immigrant children being the largest affected group.
24 citations
,
October 2019 in “Genes” In this study, the identification of a novel KAP gene in sheep, named KRTAP36-1, was associated with increased prickle factor in wool, suggesting its potential as a genetic marker for breeding purposes.
24 citations
,
January 2011 in “International Journal of Trichology” This review highlights the light microscopic features of various infectious and non-infectious hair conditions and reports no new clinical results.
24 citations
,
July 2009 in “Mycoses” This case report describes an adult patient with tinea capitis due to Microsporum canis who experienced complete hair regrowth following treatment with fluconazole and ketoconazole shampoo.
24 citations
,
March 1998 in “Mycoses” In this study, 31 children with kerion Celsi were treated successfully with antifungal medications, emphasizing the importance of early diagnosis and treatment to prevent scarring and hair loss.