research A Guide for Building Biological Pathways with Two Case Studies: Hair and Breast Development
The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
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research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Volume Rejuvenation of the Facial Upper Third
The article compares different products for rejuvenating the upper part of the face.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research Exploring the Impact of the Microbiome on Neuroactive Steroid Levels in Germ-Free Animals
Gut microbes significantly affect brain steroid levels.
research Cluster Headache: Acute and Prophylactic Therapy
Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
research Evolution And Genetic Architecture Of Sex-Limited Polymorphism In Cuckoos
Female cuckoo color differences are linked to their unique genes and help avoid male harassment.
research Medical Complications of Anorexia Nervosa and Bulimia Nervosa
Anorexia and bulimia lead to serious health problems and increased risk of death, requiring aggressive treatment.
research Dienogest
Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.
research CEO View: An Exciting Start to 2021 for The Society
The Society had a promising start to 2021 with a new online platform, grants program, and elected Trustees.
research A Cross-Cultural Ethnobotanical Knowledge Comparison About Local Plants Among Pashto, Punjabi, and Saraiki Communities Living in Southwest Pakistan
Traditional medicinal plants are still widely used and could help local development and inter-ethnic relationships.
research Proceedings of the Inaugural Pediatric Dermatology Research Alliance Conference
The conference concluded with plans for joint research into children's skin conditions and emphasized the importance of collaboration and patient-focused research.
research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study
research High-Content Drug Screening for Rare Diseases
High-content screening is useful for finding new treatments for rare diseases and has led to FDA-approved drugs.
research Characterization of Cutaneous Hormone Production Through Analysis of Skin Secretions
Skin produces different hormones depending on body part and sex, and a new method can measure them.
research A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis
Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
research Phosphodiesterase Inhibitors Used in Androgenic Alopecia as a Possible Risk Factor for Testicular Tumor
research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity
A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.
research Dermatologic Toxicities Associated with Chronic Gamma-Secretase Inhibitor Treatment for Desmoid Tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research Untargeted Metabolomics and Steroid Signatures in Urine of Male Pattern Baldness Patients After Finasteride Treatment for a Year
Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.
research MC4R Variants rs12970134 and rs17782313 Are Associated with Obese Polycystic Ovary Syndrome Patients in the Western Region of Saudi Arabia
Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
research Association of Estrogen Receptor Gene Variants (ESR1 and ESR2) with Polycystic Ovary Syndrome in Tunisia
Certain gene variants in estrogen receptors are linked to polycystic ovary syndrome, mainly affecting metabolism, in Tunisian women.
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research A Comparative Study of Different Treatment Modalities of Polycystic Ovarian Syndrome in Women of Reproductive Age Group at Tertiary Care Centre
Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.
research The Human Papillomavirus Type 11 Upstream Regulatory Region Triggers Hair-Follicle-Specific Gene Expression in Transgenic Mice
The HPV type 11 region activates hair-specific gene expression in mice.
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities
The document concludes that understanding genetic mutations in the PI3K-AKT-mTOR pathway can lead to better diagnosis and treatment for certain genetic skin disorders.
research Long-Term Epilation Using the EpiLight Broad Band, Intense Pulsed Light Hair Removal System
The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form
A genetic change in the EDAR gene causes the unique hair traits found in East Asians.