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This study found that the chemical composition and biological activity of Platycladus orientalis fruit extracts varied with the extraction method, revealing potent antioxidant and enzyme inhibitory properties, particularly in the n-hexane extract, which suggests potential applications for managing dysregulated enzyme conditions.

This study found that the water extract of Bituminaria bituminosa demonstrated the highest antioxidant activity and α-glucosidase inhibition among tested extracts, but no cholinesterase or tyrosinase inhibition.

This study found that unripe and ripe Musa sapientum fruit extracts may exhibit hypoglycemic effects by inhibiting α-amylase activity, reducing glucose diffusion, and promoting glucose uptake in yeast cells.

In this experimental study, researchers developed and optimized metformin-loaded mucoadhesive microspheres for sustained anti-hyperglycemic and anticancer activity, demonstrating high entrapment efficiency, enhanced α-amylase and α-glucosidase inhibition, improved cytotoxicity against breast cancer cells, and promising stability.

This study evaluated Tridax procumbens extracts for their in-vitro alpha amylase inhibitory activity compared to standard antidiabetic agents, suggesting potential benefits for diabetes management.

This study found that the extract of Eclipta prostrata L. demonstrated high antioxidant and anti-acetylcholinesterase activities, moderate inhibition of enzymes linked to diabetes, and favorable ADMET properties, suggesting potential cognitive and diabetes management benefits.

This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.

This study found that hydro alcoholic extract from the stem of Musa paradisiacal inhibited alpha amylase and alpha glucosidase enzymes in vitro, suggesting potential antidiabetic benefits.

This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.

This study revealed that chronic restraint stress in mice led to significant alterations in metabolic pathways and gene expression associated with hair growth inhibition, using metabolomics and transcriptomics analyses.

This study found that dabrafenib was well tolerated and led to durable responses in patients with BRAF-mutant differentiated thyroid carcinoma, with a median progression-free survival of 11.3 months.

This study found that the oral JAK1/JAK2 inhibitor deuruxolitinib effectively promoted hair regrowth and patient satisfaction in adults with alopecia areata over 24 weeks.

This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.

This study observed that glycine inhibited root growth and stimulated root hair development in habanero pepper seedlings, with ethylene signaling suggested to mediate these effects.

This review explores the phytochemistry and phytopharmacology of Urtica dioica but reports no new experimental findings, focusing on its traditional uses and range of bioactive constituents.

In this randomized, placebo-controlled trial, adults with severe chronic alopecia areata who received deuruxolitinib showed significant hair regrowth compared to placebo over 24 weeks, and the treatment was generally well-tolerated, though long-term effects remain unexamined.

In this case study, a man with Werner syndrome and diabetes saw improved glycemic control and insulin resistance with dapagliflozin, suggesting its potential usefulness for managing diabetes in similar patients.

This review highlights the significant antidiabetic activity of Allium ascalonicum (shallot), attributed to its flavonoid compounds like quercetin, in reducing blood glucose levels across various studies, while calling for further research to confirm its safety and efficacy as a diabetes treatment.

In this study, sorafenib's common adverse events, like a hand-foot syndrome and diarrhea, were observed in distinct temporal and tissue distribution patterns, revealing new relationships among effects.

This phase I study determined that a combination of oral SU-014813 and docetaxel is a feasible treatment with a manageable safety profile and potential anti-tumor activity, particularly noted in melanoma and GIST patients.

This study found that alopecia areata patients had higher baseline interleukin levels, which significantly decreased with tofacitinib treatment, though this change did not correspond to disease severity improvement.

In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.

This study suggests that human placenta hydrolysate reduces CFA-induced inflammatory pain in mice by inhibiting pro-inflammatory cytokines and protecting peripheral nerves.

In this study, researchers found that blackberry leaves exhibited higher liposoluble antioxidant levels and inhibited lipid peroxidation more effectively than raspberry leaves, while raspberry leaves showed greater water-soluble antioxidant content and hydroxyl radical inhibition in vitro.

In a laboratory study, Grateloupia elata extract demonstrated antioxidant and anti-aging effects by scavenging free radicals, inhibiting collagenase and elastase, increasing procollagen production, and reducing MMP-1 secretion, suggesting its potential use in functional cosmetics.

This study found that compounds isolated from Osmanthus fragrans var. aurantiacus demonstrated antioxidative and anti-inflammatory activities, potentially offering therapeutic benefits for inflammatory bowel diseases by inhibiting COX-2 and iNOS enzymes and blocking ERK 1/2 MAPK signaling.

This study optimized the extraction process for abomasum protein from Tianshan red deer, identifying two proteins with anti-inflammatory and anti-tumor activities, suggesting they could be beneficial in foods and nutraceuticals.

In this in vitro study, methanolic extracts of Mangifera indica and Hibiscus rosa-sinensis demonstrated significant inhibitory activity on α-amylase and α-glucosidase enzymes, suggesting their potential usefulness in diabetes management due to their comparable effects to the standard drug acarbose.

This study used computational methods to identify pranlukast and mirabegron as promising candidates for repurposing against diabetes due to their good binding interactions with the DPP-IV target.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.