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The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Loss of Fz6 disrupts hair follicle and associated structures' orientation.

Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

A protein called PLC2 is important for the growth and development of plant roots influenced by auxin.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Lupus can look like hair loss from alopecia areata but needs different treatment.

Finasteride temporarily lowers male rat fertility without affecting libido.

New compounds may soon be tested to treat excessive hair growth in women.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

Treatment during development affects hormone balance and sexual behavior in male rats.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Certain transporters are found in human hair follicles and may affect hair growth and loss.

Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.

The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.