research More Than 50 Long-Term Effects of COVID-19: A Systematic Review and Meta-Analysis
COVID-19 can cause over 50 long-term symptoms, with fatigue and headache being the most common.
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research Polycystic Ovary Syndrome, Androgen Excess, and the Risk of Nonalcoholic Fatty Liver Disease in Women: A Longitudinal Study Based on a United Kingdom Primary Care Database
Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
research Frizzled Receptors in Development and Disease
Frizzled receptors are essential for various body development processes and maintaining certain body functions.
research Nonalcoholic Fatty Liver Disease and Polycystic Ovary Syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Smoking and the Skin: Effects and Therapeutic Potential
Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
research Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line
The study used the zebrafish lateral line system to screen for compounds that induce or protect against hair cell loss, identifying 21 compounds that caused hair cell death and two compounds, PROTO1 and PROTO2, that protected against neomycin-induced damage. These findings demonstrated the zebrafish model's potential for identifying ototoxic drugs and protective agents, suggesting clinical applications for hearing protection. The research emphasized the need for standardized drug screening to prevent hearing loss and further exploration of drug delivery methods and protective pathways.
research Drug-Induced Skin, Nail, and Hair Disorders
Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.
research Efficacy And Safety Of A New Clobetasol Propionate 0.05% Foam In Alopecia Areata: A Randomized, Double-Blind Placebo-Controlled Trial
The new clobetasol propionate foam is effective and safe for treating alopecia areata.
research Effect of Aminopterin on Epithelial Tissues
Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.
research A Case-Series of 29 Patients with Lichen Planopilaris: The Cleveland Clinic Foundation Experience on Evaluation, Diagnosis, and Treatment
The study found that steroids and tetracycline helped treat active Lichen planopilaris, and hair transplants were good for later stages.
research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.
research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research Toward Understanding Scarless Skin Wound Healing and Pathological Scarring
Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
research Function and Underlying Mechanisms of Seasonal Color Molting in Mammals and Birds: What Keeps Them Changing in a Warming World?
Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
research New Antifungal Agents and Formulations Against Dermatophytes
New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.
research Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology
Platelet-rich plasma may help with hair growth and skin quality but more research is needed to confirm its effectiveness.
research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway
Applying a special compound can promote hair growth without harmful side effects.
research Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair
KGF and activin are crucial for skin healing and repair.
research Lignans and Neolignans: Plant Secondary Metabolites as a Reservoir of Biologically Active Substances
Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
research RBPJ Mutations Identified in Two Families Affected by Adams-Oliver Syndrome
Mutations in the RBPJ gene cause Adams-Oliver Syndrome.
research Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and/or Acne
Spironolactone may reduce excessive hair growth in women but its effectiveness for acne is not supported.
research Psychological Effect, Pathophysiology, and Management of Androgenetic Alopecia in Men
Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.
research Hair Growth Cycle Affects Hair Follicle Destruction by Ruby Laser Pulses
Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.
research Evaluation of Anti-Zika Virus Activities of Broad-Spectrum Antivirals and NIH Clinical Collection Compounds Using a Cell-Based, High-Throughput Screen Assay
Researchers found several compounds that could potentially treat Zika virus.
research Phenotype and Metabolic Profile of South Asian Women with Polycystic Ovary Syndrome: Results from a Specialist Endocrine Clinic
South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.
research Male-Pattern Baldness Susceptibility Locus at 20p11
Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
research Overexpression of Smad7 Results in Severe Pathological Alterations in Multiple Epithelial Tissues
Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
research Disorders Linked to Insufficient Androgen Action in Male Children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes
μ-opiate receptors in skin cells may affect skin health and healing.