206 citations
,
September 2010 in “PLoS ONE” This study found that using a Picosecond IR Laser (PIRL) on mouse skin led to less tissue damage and scarring compared to conventional surgical lasers and tools.
177 citations
,
November 2002 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, stable types of leucoderma such as segmental vitiligo and piebaldism showed 100% repigmentation after melanocyte transplantation, suggesting surgery as the preferred method for these conditions.
165 citations
,
August 2013 in “Lasers in Surgery and Medicine” This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
150 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the biological and physical principles of laser hair removal and reports that current laser systems do not consistently achieve permanent hair follicle destruction across treated areas.
137 citations
,
May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
88 citations
,
December 2018 in “Advanced Healthcare Materials” This review outlines the current state and future prospects of using layer-by-layer self-assembly for cell encapsulation in biomedical applications, such as cell-based biosensors, transplantation, and tissue engineering, while also discussing its limitations and potential advancements.
51 citations
,
October 2002 in “Archives of dermatology” This case study of a patient with dissecting cellulitis of the scalp found that multiple medications, including isotretinoin, achieved only modest improvement, and symptoms returned after treatments were stopped.
45 citations
,
December 2018 in “Lasers in Medical Science” In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.
34 citations
,
September 2007 in “Experimental Dermatology” This study found that the outer protein layer of Merino wool is rich in sulfur-containing proteins similar to those found in both sheep wool and human hair.
33 citations
,
May 2019 in “Aesthetic Plastic Surgery” This review found that most studies support the effectiveness and safety of using hyaluronic acid fillers and laser treatments together for facial rejuvenation, but highlights that the evidence is limited to small, nonrandomized studies and additional research is necessary.
31 citations
,
September 2016 in “PLoS ONE” The researchers reported that in hairless mice, epidermal cell division orientations and epidermal thickness varied by body site, with dorsal and ear epidermis primarily dividing parallel to the basement membrane, unlike hind paw and tail epidermis.
31 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.
31 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the use of the Nd:YAG laser for hair removal and reports no new research findings.
30 citations
,
June 2017 in “Talanta” This review discusses the critical parameters for MALDI IMS sample preparation in skin analysis and highlights its applications in wound healing, neoplasia, and infection research, but reports no new clinical results.
26 citations
,
June 2005 in “British Journal of Dermatology” Calretinin identifies the companion cell layer in human hair follicles.
26 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
24 citations
,
January 2016 in “Lasers in Medical Science” This study found that non-ablative fractional erbium glass laser treatment affected gene regulation in human skin models by downregulating MMP and interleukin expression, suggesting potential roles in dermal remodeling and anti-inflammatory effects.
22 citations
,
June 2002 in “Seminars in cutaneous medicine and surgery” This review discusses the use of laser and flashlamp technology for unwanted hair removal and reports no new clinical results, highlighting challenges with light-colored hair and treatment safety for darker skin tones.
20 citations
,
July 2020 in “Expert Opinion on Biological Therapy” This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.
19 citations
,
December 2015 in “Journal of Materials Chemistry B” This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” In this study, the researchers found that the effectiveness of a 1,550-nm fractional laser in promoting hair growth in mice depends on the specific combination of beam energy and density, with inappropriate settings potentially causing ulcers or hair follicle injury.
15 citations
,
June 2015 in “Lasers in Medical Science” This study found that low-level laser therapy with an 830-nm wavelength most significantly stimulated hair growth in rats, compared to other wavelengths tested.
15 citations
,
January 2003 in “Lasers in Surgery and Medicine” This study found that cold air can effectively preserve the epidermis when using an 810 nm diode laser, but it is slightly less effective than a chilled sapphire window in dark-haired pigmented pigs.
13 citations
,
July 2024 in “Medicina” This review investigates laser-induced Koebner-related reactions and highlights how different laser types, targets, and session frequencies affect the development of these skin responses, particularly in individuals with darker skin phototypes.
11 citations
,
January 2014 in “Mass spectrometry” In this study, silver oxide-based nanoparticles were used to ionize analytes and detect specific target molecules through adduct formation with silver isotopes, facilitating signal correlation with these molecules.
11 citations
,
June 2005 in “Journal of Cosmetic Dermatology” Lasers in hair transplantation show promise but are not yet standard, with current methods causing some side effects and needles still being preferred for creating recipient sites.
11 citations
,
July 2004 in “International Journal of Cosmetic Science” The conclusion is that a new method to measure hair shine was confirmed to match people's visual assessments.
10 citations
,
January 2004 in “Journal of Investigative Dermatology” Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
10 citations
,
July 1997 in “Dermatologic Clinics” This article discusses the use of laser technology in hair transplantation and highlights its potential benefits and drawbacks, emphasizing its role in achieving natural results in cosmetic hair restoration.
9 citations
,
August 2020 in “Ecological indicators” This study in western Hudson Bay, Canada, examined trace elements in the hair of adult male polar bears and found significant differences in concentration patterns along the hair length, suggesting laser ablation ICP-MS is a promising tool for monitoring these variations over time.