research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche
The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
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research Development of Fluridil, a Topical Suppressor of the Androgen Receptor in Androgenetic Alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Crystallization and Preliminary X-Ray Analysis of the Human Androgen Receptor Ligand-Binding Domain with a Coactivator-Like Peptide and Selective Androgen Receptor Modulators
Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.
research Scientific Evidence for the Cosmetic Skin and Hair Benefits of Hemp-Derived Cannabinoids: A Review
Hemp-derived cannabinoids can benefit skin and hair without causing a high.
research Phase-Specific Differential Regulation of Mechanical Allodynia in a Murine Model of Neuropathic Pain by Progesterone
Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.
research Increased Prevalence of Bipolar Disorders in Hidradenitis Suppurativa: More Than a Striking Coexistence?
People with hidradenitis suppurativa are more likely to have bipolar disorder than those with psoriasis or without skin conditions.
research Gynecologic and Hormonal Comorbidities of Scarring Alopecia: A Retrospective Review
Women with scarring alopecia are less likely to have used hormone replacement therapy or oral contraceptives compared to those with female pattern hair loss.
research Treatment of Nodulocystic Acne with Once Weekly Finasteride: A Pilot Study
research Finasteride 5mg and Sexual Side Effects: How Many Are Related to a Nocebo Phenomenon?
Knowing about finasteride's sexual side effects increases reported dysfunction.
research Non-Classic Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency Revisited: An Update with a Special Focus on Adolescent and Adult Women
The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
research Minoxidil-Induced Hair Growth Is Mediated by Adenosine in Cultured Dermal Papilla Cells: Possible Involvement of Sulfonylurea Receptor 2B as a Target of Minoxidil
Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.
research The Endocannabinoid System of the Skin: A Potential Approach for the Treatment of Skin Disorders
Targeting the skin's endocannabinoid system could help treat skin disorders.
research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study
Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
research Janus Kinase (JAK) Inhibitors for the Treatment of Skin and Hair Disorders: A Review of Literature
JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
research Hormonal Activity in Commonly Used Black Hair Care Products: Evaluating Hormone Disruption as a Plausible Contribution to Health Disparities
Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research Efficacy and Safety of 5 Alpha-Reductase Inhibitor Monotherapy in Patients with Benign Prostatic Hyperplasia: A Meta-Analysis
5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
research Novel Anti-Melanogenesis Properties of Polydeoxyribonucleotide, a Popular Wound Healing Booster
Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
research Use of H-1 Antihistamine in Dermatology: More Than Itch and Urticaria Control: A Systematic Review
H-1 antihistamines may help with various skin conditions, but more research is needed to confirm their effectiveness.
research Tumor Necrosis Factor Inhibitors and Janus Kinase Inhibitors in the Treatment of Cicatricial Alopecia: A Systematic Review
Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.
research Effectiveness, Safety, and Tolerability of Dheedhi Herbal Shampoo Against Alopecia and Seborrheic Dermatitis: A Clinical Perspective
Dheedhi Herbal Shampoo is effective and safe for treating hair loss and dandruff.
research The Prevalence and Management of Side Effects of Lithium and Anticonvulsants as Mood Stabilizers in Bipolar Disorder from a Clinical Perspective
Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.
research Identifying the Supportive Care Needs of Men and Women Affected by Chemotherapy-Induced Alopecia: A Systematic Review
People undergoing chemotherapy need better support and information to cope with hair loss.
research Ayurveda and Bioactives as Adjuvant for DNA Modulation in Cancer Treatment and Adverse Drug Reaction – A Glimpse of Traditional Indian Nanotechnology
Ayurvedic herbs may reduce side effects and improve effectiveness of cancer treatments.
research Association of Premature Hair Graying with Family History, Smoking, and Obesity: A Cross-Sectional Study
Premature hair graying in young men is linked to family history, obesity, and smoking.
research Therapeutic Indications and Use-Case-Driven Updates in the Drug Ontology: Anti-Malarials, Anti-Hypertensives, Opioid Analgesics, and a Large Term Request
The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.
research Relative Binding Affinity of Novel Steroids to Androgen Receptors in Hamster Prostate
New steroids were effective in blocking male hormone receptors in hamster prostates.
research The New Approach to Early Diagnosis of Adenomyosis
A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.
research Non-Competitive Androgen Receptor Inhibition In Vitro And In Vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
research Liposomal Packaging Generates Wnt Protein with In Vivo Biological Activity
Wnt3a protein, when packed in liposomal vesicles, can stimulate hair growth and could potentially treat conditions like hair loss.