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    Glossary Pyrilutamide

    topical treatment blocking androgen receptors to combat hair loss

    Pyrilutamide, also known as KX-826, is a topical non-steroidal anti-androgen being developed for the treatment of androgenetic alopecia (pattern hair loss). It works by blocking androgen receptors in hair follicles, which can help reduce hair loss and potentially promote hair regrowth.

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    Research 30 of 33

    1. 587 Efficacy and Safety of topical KX-826 in Male Subjects with Androgenetic Alopecia:A Multicenter, Randomized, Double-blind, Placebo-controlled Phase II Study Journal of Investigative Dermatology · 2022
    2. Development and Validation of Androgen-induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents Journal of Pharmaceutical and Pharmacological Sciences · 2024 · 1 citations
    3. The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms JEADV Clinical Practice · 2022 · 1 citations
    4. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    5. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    6. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    7. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    8. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    9. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    10. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    11. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    12. Novel DualSoftDrug Strategy Enables Developmentof Topical Androgen Receptor Antagonists with Enhanced Efficacy andOptimized Safety for Androgenetic Alopecia Figshare · 2026
    13. Novel Dual Soft Drug Strategy Enables Development of Topical Androgen Receptor Antagonists with Enhanced Efficacy and Optimized Safety for Androgenetic Alopecia Journal of Medicinal Chemistry · 2026
    14. ADVANCEMENTS IN TREATMENT STRATEGIES FOR ANDROGENETIC ALOPECIA: NOVEL THERAPIES AND FUTURE PERSPECTIVES International Journal of Innovative Technologies in Social Science · 2025
    15. The 100 most cited articles in androgenetic alopecia: A bibliometric analysis Medicine · 2025
    16. Topical solutions for androgenetic alopecia: evaluating efficacy and safety Forum Dermatologicum · 2024
    17. Androgenetic Alopecia: Therapy Update Drugs · 2023
    18. Emerging pharmacotherapies and regenerative solutions for promoting hair growth for androgenetic alopecia Frontiers in Pharmacology · 2026
    19. Who Tells the Story of the Treatment of Androgenetic Alopecia?—A Bibliometric Analysis From 2003 to 2023 Journal of Cosmetic Dermatology · 2025
    20. Emerging pharmacotherapies for Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2026
    21. A decade of progress in androgenetic alopecia management: Emerging therapies and multimodal strategies IP Indian Journal of Clinical and Experimental Dermatology · 2025
    22. Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique HAL (Le Centre pour la Communication Scientifique Directe) · 2025
    23. Androgenetic alopecia - a literature review Journal of Education Health and Sport · 2025
    24. Focused Review on Metal Nanoparticles in Hair Regeneration and Alopecia: Insights into Mechanisms, Assessment Techniques, Toxicity, Regulatory and Intellectual Property Perspectives Journal of Cluster Science · 2025
    25. Remarkable findings in male pattern baldness: sugar molecule 2dDR offers hope for hair regrowth Journal of the Pakistan Medical Association · 2025
    26. Mechanism exploration of the combined use of minoxidil with natural compounds ginsenoside Rg3 and glycyrrhizic acid for enhancing androgenic alopecia therapy Journal of Drug Delivery Science and Technology · 2025
    27. Hormonal Therapies in Cosmetic Dermatology: Mechanisms, Clinical Applications, and Future Perspectives Cosmetics · 2025 · 2 citations
    28. Androgens/Androgen Receptor in the Management of Skin Diseases Journal of Biosciences and Medicines · 2022 · 1 citations
    29. Pathophysiology of Androgenetic Alopecia and Implications for Treatment: An Overview of Current Literature Journal of Biosciences and Medicines · 2026
    30. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025