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    Glossary Piroctone Olamine

    antifungal agent used to treat dandruff and scalp conditions

    Piroctone Olamine is an antifungal agent commonly used in shampoos and other hair care products to treat dandruff and seborrheic dermatitis. It works by inhibiting the growth of the yeast Malassezia, which is often responsible for these scalp conditions. This compound is favored for its effectiveness and lower irritation potential compared to other antifungal agents like zinc pyrithione.

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    1. Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations International Journal of Cosmetic Science · 2002 · 43 citations
    2. Antidandruff hair tonic containing piroctone olamine Cosmetics and toiletries · 1988 · 4 citations
    3. Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8‐week randomized, double‐blind, placebo‐controlled clinical study International journal of cosmetic science (Print) · 2021 · 1 citations
    4. 75202 Evaluation of the anti-dandruff and soothing effect of a hair conditioner containing 0.4% piroctone olamine and niacinamide Journal of the American Academy of Dermatology · 2026
    5. Improvement in the inflammatory aspect of androgenetic alopecia. A pilot study with an antimicrobial lotion Journal of Dermatological Treatment · 1996 · 40 citations
    6. Scalp application of antioxidants improves scalp condition and reduces hair shedding in a 24‐week randomized, double‐blind, placebo‐controlled clinical trial International Journal of Cosmetic Science · 2021 · 6 citations
    7. Clear scalp, clear mind: Examining the beneficial impact of dandruff reduction on physical, emotional and social wellbeing International Journal of Cosmetic Science · 2025 · 2 citations
    8. Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff Journal of cosmetics, dermatological sciences and applications · 2013 · 2 citations
    9. Physiological Characteristics of Scalp Skin With High Sebum Production and the Impacts of Shampoo Cleansing Skin Research and Technology · 2026
    10. Clinical evaluation of the efficacy and safety of ‘ThriveCo anti-dandruff pre-shampoo treatment,’ containing ZenscalpinTM in the management of scalp dandruff in healthy adults Journal of Dermatology & Cosmetology · 2024
    11. THERAPEUTIC MANAGEMENT OF GENERALIZED CANINE DEMODICOSIS WITH SECONDARY BACTERIAL AND YEAST INFECTIONS-A CASE REPORT 2023
    12. Topical lotion beneficial in androgenetic alopecia Inpharma Weekly · 1996
    13. Study of the composition of 140 shampoos: similarities and differences depending on the sales channel used European Journal of Dermatology · 2019 · 2 citations
    14. A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis – Towards a More Precise Definition of Scalp Health Acta dermato-venereologica · 2013 · 89 citations
    15. From Telogen to Exogen: Mechanisms Underlying Formation and Subsequent Loss of the Hair Club Fiber Journal of Investigative Dermatology · 2009 · 81 citations
    16. From Axioms to New Insights into Dandruff Dermatology · 2000 · 66 citations
    17. EEMCO Guidance for the Assessment of Hair Shedding and Alopecia Skin Pharmacology and Physiology · 2004 · 51 citations
    18. Topical ketoconazole: a systematic review of current dermatological applications and future developments Journal of Dermatological Treatment · 2019 · 39 citations
    19. Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology Anais Brasileiros de Dermatologia · 2020 · 22 citations
    20. Shampoos and hair conditioners Clinics in dermatology · 1988 · 21 citations
    21. Dermoscopy Update: Review of its Extradiagnostic and Expanding Indications and Future Prospects Dermatology Practical & Conceptual · 2019 · 19 citations
    22. The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance Journal of Ethnopharmacology · 2018 · 16 citations
    23. Does tachyphylaxis occur in long‐term management of scalp seborrheic dermatitis with pyrithione zinc‐based treatments? International Journal of Dermatology · 2008 · 16 citations
    24. Roxithromycin antagonizes catagen induction in murine and human hair follicles: implication of topical roxithromycin as hair restoration reagent Archives of Dermatological Research · 2008 · 15 citations
    25. Essential of Hair Care Cosmetics Cosmetics · 2016 · 13 citations
    26. Can plant‐derived phytochemicals provide symptom relief for hair loss? A critical review International Journal of Cosmetic Science · 2019 · 10 citations
    27. Ketoconazole Shampoo for Seborrheic Dermatitis of the Scalp: A Narrative Review Cureus · 2024 · 9 citations
    28. The Inflammatory Aspect of Male and Female Pattern Hair Loss Journal of Inflammation Research · 2020 · 9 citations
    29. Effects of a new mild shampoo for preventing hair loss in Asian by a simple hand-held phototrichogram technique International Journal of Cosmetic Science · 2011 · 9 citations
    30. Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss Skin appendage disorders · 2018 · 3 citations