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    Glossary Phospholipids

    molecules forming cell membranes with hydrophilic heads and hydrophobic tails

    Phospholipids are a type of fat molecule that are essential components of cell membranes. They have a unique structure with a hydrophilic (water-attracting) "head" and two hydrophobic (water-repelling) "tails," which allows them to form the bilayer that makes up the cell membrane, providing both structural integrity and fluidity. This arrangement is crucial for various cellular functions, including signaling and substance transport.

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    1. Phospholipase A2 Is Required for PIN-FORMED Protein Trafficking to the Plasma Membrane in the<i>Arabidopsis</i>Root The Plant Cell · 2010 · 84 citations
    2. Expression and Function of Group IIE Phospholipase A2 in Mouse Skin 2016 · 26 citations
    3. Phospholipase A2 in skin biology: new insights from gene-manipulated mice and lipidomics Inflammation and Regeneration · 2018 · 24 citations
    4. Phospholipase A<sub>2</sub> inhibition as potential therapy for inflammatory skin diseases Immunotherapy · 2013 · 13 citations
    5. Design and Validation of a Sensitive Multisteroid LC-MS/MS Assay for the Routine Clinical Use: One-Step Sample Preparation with Phospholipid Removal and Comparison to Immunoassays International Journal of Molecular Sciences · 2022 · 9 citations
    6. Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant PloS one · 2012 · 8 citations
    7. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Autophagy · 2021 · 6 citations
    8. Hair Growth Promoting Potential of Phospholipids Purified from Porcine Lung Tissues Biomolecules & Therapeutics · 2015 · 3 citations
    9. Effect of Liposomes Containing Antioxidant, Phospholipid, and Amino Acid on Skin Regeneration after Chemical Burn Bulletin of Experimental Biology and Medicine · 2009 · 2 citations
    10. Phospholipase's role in maintaining and restoring skin and hair health Elsevier eBooks · 2023 · 1 citations
    11. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2022
    12. Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile Figshare · 2021
    13. The Role of Labrasol® in the Enhancement of the Cutaneous Bioavailability of Minoxidil in Phospholipid Vesicles 2012
    14. Topical Administration of Drugs Incorporated in Carriers Containing Phospholipid Soft Vesicles for the Treatment of Skin Medical Conditions Pharmaceutics · 2021 · 29 citations
    15. Phospholipid–polymer hybrid nanoparticle-mediated transfollicular delivery of quercetin: prospective implement for the treatment of androgenic alopecia Drug Development and Industrial Pharmacy · 2019 · 18 citations
    16. Co-loading of finasteride and baicalin in phospholipid vesicles tailored for the treatment of hair disorders Nanoscale · 2020 · 13 citations
    17. Coenzyme Q10 phospholipidic vesicular formulations for treatment of androgenic alopecia:<i>ex vivo</i>permeation and clinical appraisal Expert Opinion on Drug Delivery · 2021 · 10 citations
    18. Finasteride-Loaded Phospholipid-Bile Salt Mixed Micelles for Targeted Follicular Delivery in Androgenetic Alopecia. PubMed · 2026
    19. Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene <i>LIPH</i> Science · 2006 · 194 citations
    20. Phospholipase C 1 is required for skin stem cell lineage commitment The EMBO Journal · 2003 · 101 citations
    21. Phospholipase C‐δ1 is an essential molecule downstream of <i>Foxnl,</i> the gene responsible for the nude mutation, in normal hair development The FASEB Journal · 2007 · 54 citations
    22. The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2 Experimental physiology · 2023 · 6 citations
    23. Integrated Lipidomics in the Secreted Phospholipase A2 Biology International Journal of Molecular Sciences · 2011 · 11 citations
    24. [A systemic lupus erythematosus patient with multiple aseptic bone necroses, thrombosis of superior mesenteric artery and anti-phospholipid antibody]. PubMed · 1992 · 10 citations
    25. Self-aggregates of Hydrophobic Phospholipid Polymer as a Novel Material in Hair Treatment Journal of Society of Cosmetic Chemists of Japan · 2008 · 2 citations
    26. Secretory phospholipase A2-IIA overexpressing mice exhibit cyclic alopecia mediated through aberrant hair shaft differentiation and impaired wound healing response Scientific Reports · 2017 · 7 citations
    27. Different effects of phospholipase Dζ2 and non‐specific phospholipase C4 on lipid remodeling and root hair growth in Arabidopsis response to phosphate deficiency The Plant Journal · 2018 · 65 citations
    28. Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin Journal of Biological Chemistry · 2011 · 35 citations
    29. Cholesterol and Phospholipid-free Multilamellar Niosomes Regulate Transdermal Permeation of a Hydrophobic Agent Potentially Administrated for Treating Diseases in Deep Hair Follicles Journal of Pharmaceutical Sciences · 2021 · 14 citations
    30. Loss of adipocyte phospholipase gene PLAAT3 causes lipodystrophy and insulin resistance due to inactivated arachidonic acid-mediated PPARγ signaling 2021