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    Glossary PP405

    novel molecule for treating hair loss by targeting MPC

    PP405 is a novel small molecule developed by Pelage Pharmaceuticals for the treatment of hair loss, specifically targeting mitochondrial pyruvate carrier (MPC).

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    Research 27

    1. PP405 in Alopecia: An Emerging Molecule worth Investigating Journal of Community Medicine and Health Solutions · 2026
    2. Diagnostic Comparison: SH‑1 Molecule vs PP405 — Safety Profiles in Hair Science HAL (Le Centre pour la Communication Scientifique Directe) · 2026
    3. LB1045 Inhibition of pyruvate oxidation activates human hair follicle stem cells ex vivo Journal of Investigative Dermatology · 2024
    4. Review of the 2024 American Academy of Dermatology (AAD) Annual Meeting 2024
    5. Nouvelles thérapeutiques dans la prise en charge de l’alopécie androgénétique HAL (Le Centre pour la Communication Scientifique Directe) · 2025
    6. ПОРІВНЯЛЬНИЙ АНАЛІЗ МЕТОДІВ ВІДНОВЛЕННЯ ВОЛОССЯ В УКРАЇНІ ТА США Наука і техніка сьогодні · 2023
    7. Oestrogen functions in skin and skin appendages Expert Opinion on Therapeutic Targets · 2005 · 68 citations
    8. Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin PLoS ONE · 2014 · 62 citations
    9. Fatty acids and related lipid mediators in the regulation of cutaneous inflammation Biochemical Society Transactions · 2018 · 28 citations
    10. Exosomes as a novel pathway for regulating development and diseases of the skin (Review) Biomedical Reports · 2018 · 15 citations
    11. “Spigo nardo”: from the Erbario Estense a possible solution for its taxonomical attribution Rendiconti lincei. Scienze fisiche e naturali · 2018 · 4 citations
    12. Actinic Keratosis: Risk Factors, Clinical, Diagnosis and Therapeutics Aspects. Part I Dermatovenerologiâ, kosmetologiâ · 2024
    13. Study of Skin Expression of MicroRNA-146a in Patients with Alopacia Areata Benha Journal of Applied Sciences · 2018
    14. Abstracts from the 17th Congress of the European Society for Dermatology and Psychiatry Acta dermato-venereologica · 2017
    15. Clinical interest of a nonchemical lotion in head lice management Journal of The American Academy of Dermatology · 2008
    16. A case of possible Penicillium tinea capitis Archives of Dermatology · 1983
    17. Hair Melanin and Hair Color 1981 · 35 citations
    18. A Case of Possible Penicillium Tinea Capitis Archives of Dermatology · 1983 · 2 citations
    19. Emerging pharmacotherapies for Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2026
    20. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025
    21. Moxibustion improves ovarian function based on the regulation of the androgen balance Experimental and Therapeutic Medicine · 2021 · 2 citations
    22. Whole Neonatal Cochlear Explants as an <em>In vitro</em> Model Journal of visualized experiments · 2023 · 1 citations
    23. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia—A Systematic Review with Network Meta-Analyses Medicina · 2026
    24. Metabolic Engineering of Microorganisms to Produce L-Aspartate and Its Derivatives Fermentation · 2023
    25. Eosinophilic Folliculitis in a Dog ACTA SCIENTIAE VETERINARIAE · 2021
    26. Subject Index Journal of the American Academy of Dermatology · 2009
    27. Health Utility Measures Among Patients with Androgenetic Alopecia After Hair Transplant Aesthetic Plastic Surgery · 2022