In this study, mesotherapy containing nutritional supplements was found to increase patient satisfaction and improve the number of hair follicles more effectively than topical minoxidil in treating female pattern hair loss, though both methods showed similar overall efficacy in hair density and hair loss reduction.
This observational study found that mesotherapy with neonatal mesenchymal stem cells led to mild hair growth improvement in 70% of patients with androgenetic alopecia, with no major adverse events reported.
August 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
16 citations
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January 2019 in “Skin appendage disorders” This study used a network meta-analysis to compare alopecia areata treatments, finding that intralesional corticosteroids are most effective for mild cases, while diphenylcyclopropenone ranks highest for moderate to severe cases; further research on oral tofacitinib is needed.
13 citations
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January 2018 in “International Journal of Trichology” In this study, intralesional triamcinolone acetonide injections were associated with halting the progression of frontal fibrosing alopecia in female patients and showed minimal adverse effects, but the efficacy as sole therapy remains unclear pending further trials.
June 2024 in “International Journal of Research in Dermatology” This study found that combination therapy with PRP and minoxidil led to more significant improvement in androgenetic alopecia than either treatment alone, as confirmed by trichoscopic analysis.
September 2022 in “Journal of Sulaimani Medical College” In this study, the combination of topical minoxidil 5% and betamethasone valerate 0.1% achieved slightly higher depigmentation in vitiligo of hair-bearing areas but did not show significant improvement over betamethasone valerate alone.
Results are not reported for this review, which aimed to gather evidence on the effect of platelet-rich plasma monotherapy for androgenetic alopecia in men and women.
January 2019 in “Figshare” This study found that intralesional corticosteroids were most likely to produce a response in mild alopecia areata, while diphenylcyclopropenone was top-ranked for moderate to severe cases.
1 citations
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June 2020 in “Actas Dermo-Sifiliográficas” This review discusses emerging therapies for androgenetic alopecia, including topical finasteride, oral minoxidil, and intradermal dutasteride, and reports no clinical results; the authors highlight changes in treatment approaches.
1 citations
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January 2011 in “The annals of clinical and analytical medicine” This study observed that a mesotherapy formulation was associated with statistically significant improvements in hair quantity, thickness, and scalp condition among 23 patients with androgenetic alopecia, without noted side effects.
June 2026 in “Journal of Cosmetic Dermatology” This study found that hair mesotherapy containing biomimetic peptides, vitamins, and micronutrients significantly improved hair parameters in patients with androgenetic alopecia and was well-tolerated over an 8-session treatment period.
February 2026 in “Aesthetic Cosmetology and Medicine” In this case study, a 38-year-old woman with female androgenetic alopecia experienced improved hair density, reduced scalp oiliness, and enhanced hair structure after ten microneedle mesotherapy treatments combined with saw palmetto supplementation, with no adverse effects reported.
October 2025 in “Actas Dermo-Sifiliográficas” RF-mesotherapy with bicalutamide may be a promising new treatment for hair loss.
June 2025 in “Journal of Cosmetic Dermatology” This study found that among various treatments for male androgenetic alopecia, dutasteride 0.5 mg/day was the most effective option overall. Additionally, among FDA-approved treatments, topical minoxidil 5% was the most effective topical therapy, and finasteride 1 mg/day was the most effective oral therapy.
January 2022 in “Journal of Cutaneous and Aesthetic Surgery” Using truncal anesthesia on the supraorbital nerve reduces pain in hair loss treatments and improves patient comfort.
April 2008 in “Australasian journal of dermatology” The book gives a basic overview of mesotherapy and fat-dissolving injections but lacks detailed guidance and effectiveness comparisons for practitioners.
January 2018 in “Our Dermatology Online” This review summarizes the use of injectable dutasteride mesotherapy for androgenic alopecia and reports improved hair growth when combined with other substances, but highlights the need for further studies to establish long-term protocols.
12 citations
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May 2020 in “Actas Dermo-Sifiliográficas” This article discusses emerging therapies for androgenetic alopecia, highlighting the use of intradermal dutasteride, but it reports no new clinical findings.
9 citations
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November 2022 in “Journal of Cosmetic Dermatology” Among patients treated at Thomas Jefferson University, this study found that adding cryotherapy to intralesional triamcinolone acetonide (IL TAC) was more effective at reducing keloid size compared to IL TAC alone, although both treatments similarly eased pruritus and pain.
January 2025 in “Journal of Aesthetic Nursing” This review discusses the expanding role of microneedling in dermatology, highlighting its enhanced effectiveness when combined with other treatments like minoxidil, platelet-rich plasma, and exosomes, but reports no clinical results.
This study reviewed contemporary literature and found that combining minoxidil with topical finasteride, biologic adjuvants, or delivery innovations might enhance treatment effectiveness for androgenetic alopecia compared to minoxidil alone, although diverse outcomes and incomplete data limit broader conclusions.
October 2024 in “Journal of the Endocrine Society” In this retrospective chart review, researchers observed that estrogen monotherapy effectively suppressed testosterone levels below 50ng/dL in all transfeminine patients studied, particularly those using injectable formulations, though the small sample size and ongoing data collection limit these findings.
October 2024 in “Journal of the Endocrine Society” In this retrospective study, among transfeminine patients aged 19-81 receiving gender-affirming estrogen therapy, 100% achieved testosterone suppression without anti-androgens when serum estradiol exceeded 100pg/mL, predominantly using injectable estrogen.
5 citations
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April 2015 in “HSOA journal of clinical dermatology & therapy” This article reviews alopecia areata treatments, noting varied outcomes, and reports no new clinical results.
August 2026 in “Journal of Maxillofacial and Oral Surgery” This study investigated treatments for male androgenetic alopecia, finding that combining injectable platelet-rich fibrin (i-PRF) with microneedling increased hair growth more effectively than i-PRF alone according to questionnaires and photographic assessments.
December 2025 in “Journal of the European Academy of Dermatology and Venereology” January 2018 in “Sohag Medical Journal” June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
44 citations
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October 2017 in “Journal of the American Academy of Dermatology” In this study, tofacitinib monotherapy was effective in achieving hair regrowth in over half of Korean patients with moderate-to-severe and refractory alopecia areata, though treatment discontinuation typically led to hair loss recurrence.