49 citations
,
May 2020 in “The Scientific World JOURNAL” This position paper from the Italian Mesotherapy Society discusses the application of intradermal therapy based on scientific evidence, highlighting its potential benefits for certain localized conditions, although it acknowledges the lack of randomized clinical trials for some uses.
49 citations
,
July 2009 in “Journal of the American Academy of Dermatology” This report highlights two cases where patchy alopecia developed after mesotherapy for androgenetic alopecia, indicating potential risks associated with this treatment.
41 citations
,
April 2012 in “Journal of The European Academy of Dermatology and Venereology” This study found that mesotherapy with a dutasteride-containing preparation improved hair growth indicators in female pattern hair loss better than saline, with minimal side effects and greater effectiveness in patients with shorter disease duration.
34 citations
,
December 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
25 citations
,
June 2013 in “Obesity Reviews” This review examines mesotherapy for local fat reduction, detailing its mechanisms, safety concerns, and the need for research toward FDA-approved uses, but reports no new clinical findings.
25 citations
,
January 2010 in “International Journal of Trichology” This commentary reviews the controversial use of mesotherapy for androgenetic alopecia and emphasizes the need for documented evidence, without reporting new clinical results.
24 citations
,
January 2017 in “International Journal of Trichology”
23 citations
,
November 2007 in “Journal of cosmetic dermatology” This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.
20 citations
,
August 2019 in “Journal of Cosmetic Dermatology” This study reviewed literature from 1992 to 2018 to document mesotherapy-related complications and their management, concluding that standardized therapy parameters are needed to better evaluate the safety profile and minimize risks of adverse reactions.
18 citations
,
February 2017 in “Journal of Cosmetic Dermatology” This study reports that mesotherapy for androgenetic alopecia may paradoxically lead to hair loss and scarring, highlighting the need for improved regulation and monitoring of this treatment.
17 citations
,
January 2013 in “Our Dermatology Online” This study concluded that mesotherapy with a dutasteride-containing solution was the most effective option for treating androgenetic alopecia in males, promoting hair growth and reducing hair loss.
14 citations
,
January 2012 in “International Journal of Dermatology” This case report describes oleoma on the thighs and buttocks appearing two years after an injection for cellulite treatment, suggesting the need for more research to ensure the procedure's safety and efficacy.
11 citations
,
May 2019 in “Journal of Cosmetic Dermatology” This case report observed significant improvement in hair density and thickness in a male patient with androgenetic alopecia following the addition of mesotherapy, alongside topical minoxidil and oral finasteride, over 20 sessions, with no side effects reported.
11 citations
,
January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
8 citations
,
March 2022 in “Journal of Cosmetic Dermatology” This study concluded that mesotherapy appears effective for treating pattern hair loss, but emphasizes a need for more research comparing it to other treatments due to limited sample sizes.
8 citations
,
January 2008 in “PubMed” This study reports that mesotherapy can lead to serious complications, such as multifocal scalp abscesses and subcutaneous fat necrosis, requiring extensive surgical repair.
7 citations
,
January 2015 in “International Journal of Trichology” This case report describes a woman who experienced frontal edema after topical minoxidil application following mesotherapy, noting that excessive absorption of minoxidil may cause localized vasodilatory side effects.
6 citations
,
November 2017 in “Journal of the European Academy of Dermatology and Venereology” A woman got melanoma on her scalp after anti-hair loss treatment with injections.
5 citations
,
July 2025 in “Journal of Clinical Medicine” This study reviewed existing literature on mesotherapy and developed evidence-based guidelines, which support its standardized and safe use for osteoarticular pain, rehabilitation, and dermatology, marking a shift from practice based on personal beliefs to an evidence-based approach.
5 citations
,
February 2021 in “Gels” In this study, HYDRO DELUXE BIO was reported to show promise for scalp mesotherapy by enhancing angiogenesis and reducing inflammation in an in vitro model.
5 citations
,
February 2021 in “Dermatology and Therapy” This study found that two sessions of platelet-rich plasma mesotherapy significantly improved symptoms in patients with corticosteroid-induced rosacea-like dermatitis without further treatment.
5 citations
,
July 2020 in “Journal of Cosmetic Dermatology” This study found that using a vibration anesthetic device during scalp mesotherapy significantly reduced pain in patients with androgenetic alopecia and alopecia areata compared to the non-vibration side.
4 citations
,
December 2021 in “Dermatologic Therapy” This study reported 14 cases of frontal edema following mesotherapy for androgenetic alopecia, suggesting clinicians should be aware of this potential side effect.
3 citations
,
April 2011 in “Expert Review of Dermatology” This review discusses the use of mesotherapy, highlighting its popularity and the lack of large, randomized controlled trials, and advises cautious use.
3 citations
,
June 2007 in “CRC Press eBooks” Mesotherapy might be an effective treatment for hair loss.
3 citations
,
April 2021 in “Journal of Cosmetic Dermatology” Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.
2 citations
,
July 2023 in “Journal of Education Health and Sport” This review article summarizes potential side effects of microneedle mesotherapy, including both infectious and non-infectious complications such as bruises, swelling, anaphylaxis, and skin necrosis, emphasizing that awareness and proper technique may mitigate these risks.
2 citations
,
April 2017 in “Health technology assessment in action” This study reviewed previous research and found that while mesotherapy appears to improve outcomes in treating androgenetic alopecia without significant adverse effects, the supporting studies were of poor quality, and further research is necessary to confirm its efficacy and safety.
2 citations
,
May 2015 in “International Journal of Scientific Reports” In this observational study, 95% of androgenetic alopecia patients treated with neonatal mesenchymal stem cells through mesotherapy showed mild to moderate improvement in hair growth and reduction in hair loss.
2 citations
,
March 2014 in “Turkderm” Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.