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Glossary LaserComb

handheld device using low-level laser therapy to stimulate hair growth

A LaserComb, also known as a Laser Hair Comb, is a handheld device that uses low-level laser therapy (LLLT) to stimulate hair follicles and promote hair growth. It is often used as a treatment for androgenetic alopecia (pattern hair loss) and works by increasing blood flow and cellular activity in the scalp.

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Low-Level Laser Therapy for Treatment of Hair Loss

research Low‐level laser (light) therapy (LLLT) for treatment of hair loss

165 citations , August 2013 in “Lasers in Surgery and Medicine”

This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.

Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study

research Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study

147 citations , January 2014 in “American Journal of Clinical Dermatology”

This study found that low-level laser treatment with the HairMax Lasercomb significantly increased terminal hair density in both men and women with pattern hair loss, with no serious adverse events reported.

research Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata

81 citations , July 2011 in “Lasers in Medical Science”

This study found that using a low-level laser comb led to hair regrowth in a mouse model of alopecia areata, while sham-treated mice showed no hair regrowth.

research The growth of human scalp hair in females using visible red light laser and LED sources

81 citations , August 2014 in “Lasers in Surgery and Medicine”

This study found that low-level laser therapy significantly increased hair growth in women with androgenic alopecia, achieving a 37% greater increase in hair counts compared to placebo.

research Low level laser therapy and hair regrowth: an evidence-based review

60 citations , December 2015 in “Lasers in Medical Science”

This review concluded that FDA-cleared low-level laser therapy devices are safe and effective for patients with male and female pattern hair loss who do not respond to or tolerate standard treatments.

research Alopecia: A review of laser and light therapies

40 citations , February 2012 in “Dermatology Online Journal”

This review discusses cases and research on paradoxical hair growth after laser hair removal and explores laser and light therapies for treating alopecia, but reports no new results.

research Novel Approach to Treating Androgenetic Alopecia in Females With Photobiomodulation (Low-Level Laser Therapy)

33 citations , March 2017 in “Dermatologic Surgery”

In this clinical study, low-level laser therapy using the HANDI-DOME LASER device increased hair counts by 51% compared to controls, indicating its potential as a safe and effective treatment for androgenetic alopecia in women aged 18 to 60.

research A Critical Assessment of the Evidence for Low-Level Laser Therapy in the Treatment of Hair Loss

32 citations , September 2016 in “Dermatologic Surgery”

This review discusses the current evidence and highlights gaps in research needed for the wider acceptance of low-level laser therapy as a treatment for hair loss; no new clinical results are provided.

Comparison of the Effects of 665 nm Low-Level Diode Laser Hat Versus a Combination of 665 nm and 808 nm Low-Level Diode Laser Scanner on Hair Growth in Androgenic Alopecia

research Comparison of the effects of 665 nm low level diode Laser Hat versus and a combination of 665 nm and 808nm low level diode Laser Scanner of hair growth in androgenic alopecia

24 citations , May 2017 in “Journal of Cosmetic and Laser Therapy”

This study reported that a new laser scanner using 655 nm red and 808 nm infrared lasers significantly improved hair density in patients with androgenic alopecia compared to both a laser hat and no treatment, without observable adverse effects.

research Lack of Response to Laser Comb in Spontaneous and Graft-Induced Alopecia Areata in C3H/HeJ Mice

13 citations , January 2014 in “Journal of Investigative Dermatology”

The laser comb did not improve hair regrowth in mice with alopecia areata.

research No improvement in male-pattern hair loss using laser hair-comb therapy: a 6-month, half-head, assessor-blinded investigation in two men

13 citations , October 2011 in “Clinical and Experimental Dermatology”

This study found no improvement in male-pattern hair loss after six months of using laser hair-comb therapy in two men.

research Examining the Safety and Efficacy of Low-Level Laser Therapy for Male and Female Pattern Hair Loss: A Review of the Literature

11 citations , January 2020 in “Skin appendage disorders”

This study reviewed clinical trials and found that low-level laser therapy significantly increased hair diameter or density in both men and women with pattern hair loss compared to a sham device, though the involvement of industry relationships in some studies suggests cautious interpretation.

The Effect of One Session Low Level Laser Therapy on Extracted Follicular Units in Hair Transplantation

research The Effect of One Session Low Level Laser Therapy of Extracted Follicular Units on the Outcome of Hair Transplantation

6 citations , January 2016 in “Journal of lasers in medical sciences”

This study found that a single session of low level laser irradiation did not significantly affect hair growth outcomes in transplanted follicles for patients with androgenic alopecia.

research At-Home Laser and Light-Based Devices

4 citations , January 2011 in “Current problems in dermatology”

This article reviews the growing trend of at-home laser and light devices for treating conditions like acne, hair removal, and psoriasis, emphasizing their popularity and the need for cautious use but reports no new clinical results.

research STIMULATION OF HAIR REGROWTH USING LOW LEVEL LASER TREATMENT IN A RAT MODEL OF ALOPECIA

January 2013

This study found that in a rat model of alopecia, combining low-level laser therapy with Neoptide treatment resulted in better hair regrowth compared to either treatment used alone.

research Efficacy and Safety of Laser Therapy and Phototherapy in Cicatricial and NonCicatricial Alopecia: A Systematic Review Study

November 2024 in “Health Science Reports”

This systematic review found that light and laser therapies, including excimer and erbium-glass lasers, generally increase hair density and diameter in various types of alopecia, with particularly notable effects in androgenic alopecia but limited efficacy in telogen effluvium.

research Láser de baja potencia para tratar la alopecia androgénica

6 citations , October 2020 in “Actas Dermo-Sifiliográficas”

This review discusses the effectiveness of low-level laser therapy for androgenetic alopecia, finding significant increases in hair density and growth for individuals treated with this method.

research Low-level laser/light therapy for androgenetic alopecia.

2 citations , September 2014 in “PubMed”

This review discusses low-level laser or light devices as an alternative treatment for androgenetic alopecia and highlights the need for further research to compare their efficacy with existing therapies.

research Laser therapies in androgenetic alopecia: Review and clinical experiences

January 2025 in “Journal of Cutaneous and Aesthetic Surgery”

This review indicates that various laser therapies, alone or combined with other treatments, show potential in improving hair density and treating androgenetic alopecia, but outcomes can vary, underscoring the importance of personalized treatment.

research Chapter 14 Low-Level Laser Therapy and Stem Cells

August 2016

This study found that low-level laser therapy may enhance wound healing and reduce pain, swelling, and inflammation by increasing mitochondrial activity and oxidative stress, leading to greater protein synthesis and cell proliferation.

research HairMax LaserComb® Laser Phototherapy Device in the Treatment of Male Androgenetic Alopecia

160 citations , January 2009 in “Clinical Drug Investigation”

This study found that the HairMax LaserComb® significantly increased hair density and was safe and well tolerated for treating androgenetic alopecia in men compared to a sham device.

research Hair Regrowth and Increased Hair Tensile Strength Using the HairMax LaserComb for Low-Level Laser Therapy

75 citations , August 2003 in “International journal of cosmetic surgery and aesthetic dermatology”

This study found that low level laser therapy with a HairMax LaserComb improved hair counts and tensile strength in patients with androgenetic alopecia, particularly in males and vertex areas.

research Low-level laser therapy as a treatment for androgenetic alopecia

47 citations , April 2016 in “Lasers in Surgery and Medicine”

This review found that low-level laser therapy appears promising in improving hair regrowth and patient satisfaction in androgenetic alopecia, though results should be interpreted cautiously.

research A Review of Hand-Held, Home-Use Cosmetic Laser and Light Devices

24 citations , March 2015 in “Dermatologic Surgery”

This review discusses the modest efficacy of home-use laser and light devices for conditions like hair removal and acne, noting limited evidence and a lack of robust trials.

research Evaluation of Efficacy of Low-Level Laser Therapy

64 citations , October 2020 in “Journal of lasers in medical sciences”

This review discusses the benefits and drawbacks of low-level laser therapy for various non-surgical conditions based on existing literature, but reports no new clinical findings and suggests further research is needed.

Low-Level Laser Therapy for the Treatment of Androgenetic Alopecia in Thai Men and Women: A 24-Week, Randomized, Double-Blind, Sham Device-Controlled Trial

research Low-level laser therapy for the treatment of androgenetic alopecia in Thai men and women: a 24-week, randomized, double-blind, sham device-controlled trial

45 citations , December 2018 in “Lasers in Medical Science”

In a 24-week randomized trial, this study found that the RAMACAP laser helmet significantly increased hair density and diameter in androgenetic alopecia patients compared to a sham device, although limitations included a small sample size and potential issues with the control used.

research Use of low-level laser therapy as monotherapy or concomitant therapy for male and female Androgenetic alopecia

45 citations , January 2014 in “International Journal of Trichology”

This study found that low-level laser therapy may improve hair growth in patients with androgenetic alopecia, either as a standalone treatment or combined with minoxidil or finasteride, without reported adverse reactions.

research Erbium–Yttrium–Aluminum–Garnet Laser Irradiation Ameliorates Skin Permeation and Follicular Delivery of Antialopecia Drugs

31 citations , September 2014 in “Journal of Pharmaceutical Sciences”

This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.

research Evaluation of wavelength-dependent hair growth effects on low-level laser therapy: an experimental animal study

15 citations , June 2015 in “Lasers in Medical Science”

This study found that low-level laser therapy with an 830-nm wavelength most significantly stimulated hair growth in rats, compared to other wavelengths tested.

research Systematic review of low-level laser therapy for adult androgenic alopecia

13 citations , December 2017 in “Journal of Cosmetic and Laser Therapy”

This study evaluated the use of low-level laser therapy for treating androgenic alopecia in adults, finding it a promising and safe at-home option for stimulating hair growth compared to sham devices, though further research is needed to confirm its clinical effectiveness.