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    Glossary Hydroquinone

    skin-lightening agent used to treat hyperpigmentation

    Hydroquinone is a skin-lightening agent commonly used in dermatology to treat hyperpigmentation conditions such as melasma, age spots, and acne scars. It works by inhibiting the enzyme tyrosinase, which is essential for the production of melanin, the pigment responsible for skin color.

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    Research 30 of 365

    1. Effects of Skin Lightening Cream Agents – Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats Clinical Cosmetic and Investigational Dermatology · 2020 · 46 citations
    2. The first clinical experience on efficacy of topical flutamide on melasma compared with topical hydroquinone: a randomized clinical trial Drug Design Development and Therapy · 2015 · 38 citations
    3. A pilot study for triple combination therapy with a low-fluence 1064 nm Q-switched Nd:YAG laser, hydroquinone cream and oral tranexamic acid for recalcitrant Riehl’s Melanosis Journal of dermatological treatment · 2016 · 36 citations
    4. Diagnostic utility of dermatoscopy in hydroquinone‐induced exogenous ochronosis International Journal of Dermatology · 2012 · 34 citations
    5. The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone 2017 · 23 citations
    6. Co-Drug Strategy for Promoting Skin Targeting and Minimizing the Transdermal Diffusion of Hydroquinone and Tranexamic Acid Current medicinal chemistry · 2013 · 21 citations
    7. The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model International journal of pharmaceutics · 2014 · 18 citations
    8. Therapeutic effects of topical Mycophenolate mofetil on hydroquinone-induced depigmentation in Guinea pigs and mice Annals of Medicine · 2025
    9. An Open-Label Comparative Study on the Effects of Platelet-Rich Plasma Therapy with Hydroquinone 4% Versus Hydroquinone 4% Alone in Melasma Dermatology Review · 2024
    10. 018 IMPACT OF COSMETIC PRODUCTS WITH HYDROQUINONE ON THE MEASURE OF CAPILLARY BLOOD SUGAR IN DIABETIC SENEGALESE WOMEN: CASE CONTROL STUDY Journal of Investigative Dermatology Symposium Proceedings · 2017
    11. Comparative evaluation for the efficacy and tolerance of two skin products containing either hydroquinone or emblica extract with kojic acid in female subjects with facial dyschromia Journal of the American Academy of Dermatology · 2009
    12. Lymphocytic Infiltration of the Skin Jessner-Kanof After Treatment With a Hydroquinone-Containing Bleaching Cream Archives of dermatology · 2006 · 20 citations
    13. Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles Pharmaceutical research · 2012 · 43 citations
    14. Solar-Induced Postinflammatory Hyperpigmentation after Laser Hair Removal Dermatologic surgery · 1999 · 31 citations
    15. Vesicles: Potential nano carriers for the delivery of skin cosmetics Journal of Cosmetic and Laser Therapy · 2017 · 21 citations
    16. Glycine Inhibits Melanogenesis in Vitro and Causes Hypopigmentation in Vivo Biological & pharmaceutical bulletin · 2007 · 19 citations
    17. Pigmentation and Pregnancy Obstetrics & Gynecology · 2016 · 15 citations
    18. 1927 nm Thulium Laser Successfully Treats PostInflammatory Hyperpigmentation in Skin of Color Dermatology Research and Practice · 2021 · 12 citations
    19. Topical and Systemic Therapies in Melasma: A Systematic Review Indian Dermatology Online Journal · 2023 · 10 citations
    20. Safety of skin care products during pregnancy. PubMed · 2011 · 10 citations
    21. Melasma and other skin manifestations or oral contraceptives. PubMed · 1967 · 10 citations
    22. Practical approaches to medical and cosmetic dermatology in skin of color patients Expert review of dermatology · 2011 · 7 citations
    23. Influence of Depigmenting Chemical Agents on Hair and Skin Color in Yellow (Pheomelanic) and Black (Eumelanic) Mice Pigment Cell Research · 1990 · 7 citations
    24. Treatment of Exogenous Ochronosis With Advanced Fluorescence Technology Dermatologic surgery · 2014 · 5 citations
    25. Efficacy and Safety of Platelet-Rich Plasma in Melasma: A Systematic Review Cureus · 2024 · 3 citations
    26. Topical <i>Cyperus rotundus</i> essential oil for treatment of axillary hyperpigmentation: a randomized, double‐blind, active‐ and placebo‐controlled study Clinical and experimental dermatology · 2021 · 2 citations
    27. Unmasking Melasma: Confronting the Treatment Challenges Cosmetics · 2024 · 1 citations
    28. Melasma in Men Journal of Pigmentary Disorders · 2015 · 1 citations
    29. Cosmeceuticals in Dermatology Springer eBooks · 2013 · 1 citations
    30. Evolution Of Anti-Hyperpigmentation Skincare: From Traditional Remedies To Modern Cosmeceutical Approaches For Adolescents Adolescencia e Saude · 2026