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    Glossary HMI-115

    HMI-115 is an investigational drug designed to target hair loss by promoting hair follicle regeneration and preventing further hair thinning. It works by modulating specific pathways involved in hair biology, particularly those related to the growth phase of hair follicles. This compound is relevant in the context of androgenetic alopecia and other forms of hair loss, as it aims to provide a novel therapeutic option that differs from traditional treatments like minoxidil and finasteride. Key distinguishing characteristics of HMI-115 include its unique mechanism of action and its potential to stimulate hair growth without the side effects commonly associated with existing hair loss treatments.

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    Research 30 of 65

    1. The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms JEADV Clinical Practice · 2022 · 1 citations
    2. A Study on the Effectiveness and Safety of Herbal Extract Combination Compared to 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A Randomized, Double-blind, Controlled Trial ˜The œOpen dermatology journal · 2024
    3. Emerging pharmacotherapies for Androgenetic Alopecia Expert Opinion on Pharmacotherapy · 2026
    4. A dietary supplement improves age-related dermatological changes. Observational, anecdotal, spontaneous study. Asian journal of medical sciences · 2017 · 1 citations
    5. Topical application of the Wnt/<i>β</i>-catenin activator methyl vanillate increases hair count and hair mass index in women with androgenetic alopecia Journal of Cosmetic Dermatology · 2016 · 20 citations
    6. Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth Plastic and Aesthetic Research · 2021 · 3 citations
    7. Effects of a New Topical Treatment Containing Several Hair Growth Promoters in Women with Early Female Pattern Hair Loss Skin appendage disorders · 2018 · 3 citations
    8. Hypotensive Activity and Toxicology of Constituents from Bombax ceiba Stem Bark. Biological & Pharmaceutical Bulletin · 2003 · 58 citations
    9. A Segmental Approach to Scoring Hair Density from Global Images: Introducing the Scalp Coverage Scoring Method for Clinical Trials and Practice Nature Cell and Science · 2024
    10. The pathophysiology of polycystic ovary syndrome: trying to understand PCOS and its endocrinology Best Practice & Research in Clinical Obstetrics & Gynaecology · 2004 · 131 citations
    11. Androgens in SARS-CoV-2 Coronavirus Infections Physiological Research · 2021 · 5 citations
    12. Comparative overview of phytoconstituents and pharmacological potential of Trigonella foenum-graecum leaves and seeds International Journal of Ayurvedic Medicine · 2025
    13. From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization Frontiers in Cell and Developmental Biology · 2026
    14. Dermal EZH2 simultaneously orchestrates dermal differentiation and epidermal proliferation during murine skin development bioRxiv (Cold Spring Harbor Laboratory) · 2020
    15. Dermal EZH2 simultaneously orchestrates Wnt/β-catenin signaling dependent dermal differentiation and retinoic acid signaling dependent epidermal proliferation during murine skin development bioRxiv (Cold Spring Harbor Laboratory) · 2020
    16. <i>Sept4/</i> ARTS Regulates Stem Cell Apoptosis and Skin Regeneration Science · 2013 · 78 citations
    17. Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p 2025
    18. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia—A Systematic Review with Network Meta-Analyses Medicina · 2026
    19. An Open-Label Evaluator Blinded Study of the Efficacy and Safety of a New Nutritional Supplement in Androgenetic Alopecia: A Pilot Study. PubMed · 2017 · 1 citations
    20. Optimizing Scalp Cooling: (Ultra)Structural Follicular Characteristic and Restorative Advances Cancer Management and Research · 2025
    21. Efficacy of a cosmetic product mimicking PRP in androgenetic alopecia Journal of translational science · 2020
    22. Molecular Mechanisms and Targeted Therapeutics in Androgenetic Alopecia: From Signaling Pathways to Regenerative Approaches Premier journal of science. · 2026
    23. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025
    24. Recent approaches of antibody therapeutics in androgenetic alopecia Frontiers in Pharmacology · 2024
    25. What Can Complex Dietary Supplements Do for Hair Loss and How Can It Be Validly Measured—A Review Applied Sciences · 2020 · 8 citations
    26. Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development Developmental biology · 2021 · 6 citations
    27. Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy Nanoenergy Advances · 2025 · 2 citations
    28. Nanogenerators in Biomedical Frontiers: Revolutionizing Self-Powered Healthcare Systems ACS Omega · 2026 · 1 citations
    29. Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair—What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns Cosmetics · 2025
    30. Musculoskeletal and body composition response to high-dose testosterone with finasteride after chronic incomplete spinal cord injury—a randomized, double-blind, and placebo-controlled pilot study Frontiers in Neurology · 2024