5 citations,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
January 2017 in “Clinical & medical biochemistry” Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.
204 citations,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
January 2024 in “International journal of molecular sciences” A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.
January 2014 in “Side effects of drugs annual” Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
March 2024 in “The journal of sexual medicine” The therapies improved ejaculation disorders and sexual function in middle-aged men.
30 citations,
December 1999 in “Journal of Investigative Dermatology Symposium Proceedings” Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
5 citations,
May 2023 in “Science of the total environment” PFAS exposure in adolescence may delay puberty in females.
19 citations,
March 1994 in “Fertility and sterility” The combination therapy reduced hirsutism in women with PCOD and was well-tolerated.
9 citations,
May 2019 in “Experimental Cell Research” HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
September 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher SHBG levels are linked to less severe hair loss in women, but vitamin D levels don't seem to affect hair loss.
7 citations,
January 2015 in “Case reports in endocrinology” The document concludes that HAIR-AN syndrome should be considered when a patient shows severe hyperandrogenism and insulin resistance after excluding tumors.
36 citations,
May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
11 citations,
July 2019 in “The Journal of Sexual Medicine” Spironolactone might cause painful intercourse and decreased sexual arousal in women.
28 citations,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
14 citations,
June 2015 in “Toxicology and Industrial Health” Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
36 citations,
October 2016 in “Bone” A male with aromatase deficiency improved bone health with estradiol treatment.
A new lipid-based formula using myristyl myristate can improve estradiol treatment for hair loss.
1 citations,
October 2022 in “Evidence-based Complementary and Alternative Medicine” Traditional Chinese Medicine may help treat hair loss but needs more research.
23 citations,
January 2016 in “Transgender health” Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
17 citations,
February 2003 in “Australasian Journal of Dermatology” Hair loss in postmenopausal woman caused by ovarian issue.
June 2023 in “The journal of sexual medicine” The treatment helped a transgender woman stop drinking, improved her mental health, and reduced her gender dysphoria.
February 2025 in “Actas Dermo-Sifiliográficas” Transgender patients with hair loss need personalized treatment plans considering their unique needs.
74 citations,
February 2018 in “Stroke” Women have unique stroke risks due to hormones, contraceptives, pregnancy, and menopause.
4 citations,
January 1994 in “Journal of hepatology” Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.
Testosterone in human pancreas cells boosts insulin production.
1 citations,
May 2019 in “The Journal of Sexual Medicine” Spironolactone may cause sexual pain and arousal issues in women, which can improve after stopping the drug and using hormone cream.
88 citations,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
67 citations,
January 2007 in “Climacteric” Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
8 citations,
March 2008 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.