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    Glossary Cyproterone

    medication that blocks male hormones to treat various conditions

    Cyproterone, often referred to as Cyproterone acetate or Androcur, is a medication that acts as an anti-androgen. It works by blocking the effects of male hormones (androgens) in the body, which can be useful in treating conditions like severe acne, hirsutism (excessive hair growth), and certain types of prostate cancer. It is also used in hormone therapy for transgender women.

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    1. Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism Journal of Steroid Biochemistry · 1975 · 232 citations
    2. Effects of minoxidil 2% vs. cyproterone acetate treatment on female androgenetic alopecia: a controlled, 12-month randomized trial British Journal of Dermatology · 2002 · 149 citations
    3. Pharmacology and Potential Use of Cyproterone Acetate Hormone and metabolic research · 1977 · 129 citations
    4. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999 · 113 citations
    5. Cyproterone acetate for severe hirsutism:results of a double‐blind dose‐ranging study* Clinical endocrinology · 1991 · 94 citations
    6. Risk of meningioma among users of high doses of cyproterone acetate as compared with the general population: evidence from a population-based cohort study British Journal of Clinical Pharmacology · 2011 · 88 citations
    7. The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in women Clinical Endocrinology · 1992 · 83 citations
    8. Cyproterone acetate for hirsutism Cochrane library · 2003 · 78 citations
    9. The effect of 2 combined oral Contraceptives containing either drospirenone or cyproterone acetate on acne and seborrhea. PubMed · 2002 · 74 citations
    10. Comparison of Sequential Cyproterone Acetate/Estrogen Versus Spironolactone/Oral Contraceptive in the Treatment of Hirsutism 1991 · 68 citations
    11. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    12. Use of high dose cyproterone acetate and risk of intracranial meningioma in women: cohort study BMJ · 2021 · 59 citations
    13. The Evaluation of the Role of Androgens in Hirsutism and the Use of a New Anti-androgen “Cyproterone Acetate” for Therapy 1974 · 58 citations
    14. Use of cyproterone acetate, finasteride, and spironolactone to treat idiopathic hirsutism Fertility and Sterility · 2003 · 56 citations
    15. Liarozole—a novel treatment approach for advanced prostate cancer: results of a large randomized trial versus cyproterone acetate Urology · 1998 · 52 citations
    16. Comparison of cyproterone acetate plus ethinyl estradiol and finasteride in the treatment of hirsutism Journal of Endocrinological Investigation · 1998 · 49 citations
    17. Gonadotrophin-releasing hormone agonist therapy for hirsutism is as effective as high dose cyproterone acetate but results in a longer remission Human reproduction · 1997 · 49 citations
    18. A combined regimen of cyproterone acetate and testosterone enanthate as a potentially highly effective male contraceptive. The Journal of Clinical Endocrinology and Metabolism · 1996 · 49 citations
    19. 11 Treatment of hirsutism and acne with cyproterone acetate Clinics in Endocrinology and Metabolism · 1986 · 43 citations
    20. Treatment of hirsutism and acne in women with two combinations of cyproterone acetate and ethinylestradiol. PubMed · 1976 · 42 citations
    21. Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting Pharmaceutical development and technology · 2019 · 40 citations
    22. Treatment of Hirsutism, Acne and Alopecia with Cyproterone Acetate Dermatology · 1980 · 39 citations
    23. Finasteride versus cyproterone acetate-estrogen regimens in the treatment of hirsutism International journal of gynaecology and obstetrics · 2004 · 39 citations
    24. Consecutive Cyproterone Acetate and Estradiol Treatment in Late-Pubertal Transgender Female Adolescents ˜The œjournal of sexual medicine · 2017 · 36 citations
    25. Presentation of a meningioma in a transwoman after nine years of cyproterone acetate and estradiol intake: case report and literature review Gynecological Endocrinology · 2017 · 34 citations
    26. Cyproterone Acetate in the Treatment of Sexual Disorders: Pharmacological Base and Clinical Experience Experimental and clinical endocrinology & diabetes · 2009 · 30 citations
    27. Oral Contraceptives and Cyproterone Acetate in Female Acne Treatment Dermatology · 1998 · 30 citations
    28. Effect of cyproterone acetate on rate of hair growth in hirsute females 1981 · 26 citations
    29. A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism The Journal of Clinical Endocrinology and Metabolism · 1999 · 23 citations
    30. Effectiveness of Anastrozole and Cyproterone Acetate in Two Brothers with Familial Male Precocious Puberty Journal of Pediatric Endocrinology and Metabolism · 2008 · 21 citations