research Synthesis and Application of Clinically Approved Small-Molecule Drugs Targeting Androgen Receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
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research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research The State-of-the-Art in the Management of Androgenetic Alopecia: A Review of New Therapies and Treatment Algorithms
New and existing treatments for hair loss show promise, with some being more effective for men and others for women.
research Combination of Oral Minoxidil and Bicalutamide for the Treatment of Female Pattern Hair Loss in Adolescents
Combining oral minoxidil and bicalutamide may help improve hair growth in adolescent girls.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Polycystic Ovary Syndrome: Manifestation and Treatment Strategies
Polycystic ovary syndrome affects health and can be hard to diagnose, with treatments ranging from drugs to herbal remedies.
research A Systematic Review of Antiandrogens and Feminization in Transgender Women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Mesotherapy With Bicalutamide: A New Treatment for Androgenetic Alopecia
Bicalutamide mesotherapy may help with hair loss and seborrhea but needs more research.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Frontal Fibrosing Alopecia After Antiandrogen Hormonal Therapy in a Male Patient
A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
research Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients
Oral bicalutamide is safe and effective for female hair loss.
research The Hormonal Background of Hair Loss in Non-Scarring Alopecias
Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.
research Update on Idiopathic Hirsutism: Diagnosis and Treatment
The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
research Bicalutamide and the New Perspectives for Female Pattern Hair Loss Treatment: What Dermatologists Should Know
Bicalutamide, a drug with a good safety profile, is a promising new treatment for female pattern hair loss.
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
research Oral Bicalutamide for Female Pattern Hair Loss: A Pilot Study
Bicalutamide improves hair density in women safely.
research Bicalutamide 25 Mg Associated With Minoxidil 1 Mg Versus Minoxidil 1 Mg for Female-Pattern Hair Loss: A Randomized Double-Blind Clinical Trial
research Comment on: Bicalutamide and the New Perspectives for Female Pattern Hair Loss Treatment: What Dermatologists Should Know
research Reply to: Comment on Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients
research Faculty Opinions Recommendation of Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Androgenetic Alopecia, Prostate Volume, And Urinary Symptoms: Is There A Relationship? A Case-Control Study
Hair loss, prostate size, and urinary issues are related due to androgen effects.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
research Enzalutamide, a Prostate Cancer Therapeutic, Downregulates TMPRSS2 in Lung and Reduces Cellular Entry of SARS-CoV-2
Enzalutamide, a prostate cancer drug, may help prevent COVID-19 by blocking the virus from entering lung cells.
research Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies
Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
research Spironolactone in the Treatment of Hirsutism
Spironolactone was effective in reducing hair growth in women with hirsutism.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Abstract P5-09-21: Selective Androgen Receptor Modulators (SARMs): Enobosarm as Targeted Therapy for the Treatment of Androgen Receptor-Positive Breast Cancer
Enobosarm may effectively treat androgen receptor-positive breast cancer with fewer side effects.
research Hair Growth Effect and the Mechanisms of Rosa Rugosa Extract in DHT-Induced Alopecia Mice Model
Rosa rugosa extract promotes hair growth and could be a natural treatment for hair loss.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.