45 citations,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
7 citations,
May 2005 in “Experimental Dermatology” Two mouse mutations cause similar hair loss despite different skin changes.
34 citations,
December 2012 in “Indian Journal of Dermatology, Venereology and Leprology” Mesotherapy shows promise for cellulite and facial rejuvenation but has mixed results for body sculpting and hair loss, with more research needed for safety and effectiveness.
116 citations,
December 2017 in “International Journal of Women's Dermatology” Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
84 citations,
December 2008 in “Developmental biology” Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
4 citations,
December 2012 in “Human Biology” The most different genetic segment between Africans and East Asians is the EDA2R/AR region, with two main types influenced by population changes and natural selection, and linked to baldness.
7 citations,
January 2018 in “Neurodegenerative Diseases” Researchers found a new ABCD1 gene mutation linked to a rare brain and nerve disorder with unusual brain changes.
7 citations,
August 2020 in “Current topics in medicinal chemistry” New cancer treatments aim to reduce side effects and improve effectiveness.
1707 citations,
December 2003 in “The New England Journal of Medicine” Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
25 citations,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
13 citations,
December 2010 in “Annales de Dermatologie et de Vénéréologie” The conclusion is that skin, mucous, and eye problems after Stevens-Johnson syndrome and Lyell syndrome significantly affect patients' lives, highlighting the need for comprehensive care and eye check-ups.
January 2018 in “Springer eBooks” The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.
14 citations,
December 2010 in “Journal of human genetics” A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.
January 2018 in “Elsevier eBooks” Topical imiquimod is as effective as 5-fluorouracil for treating actinic keratosis, with about a 5% risk of it turning into squamous cell carcinoma.
7 citations,
September 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” Occipital donor sites for skin grafts heal faster, hurt less, look better, and have fewer complications than femoral sites.
7 citations,
May 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
7 citations,
February 2004 in “Clinical and Experimental Ophthalmology” Finasteride, often used for hair loss, can potentially cause cataracts.
16 citations,
December 2008 in “International Journal of Dermatology” Long-term use of pyrithione zinc shampoos remains effective for scalp seborrheic dermatitis, with decreased effectiveness likely due to not following treatment instructions rather than the treatment itself.
9 citations,
June 2008 in “Springer eBooks” Understanding hair follicle structure is key for treating hair disorders and could help develop new treatments.
32 citations,
December 2017 in “Journal of Drug Delivery Science and Technology” Minoxidil and caffeine in transfersomes improve hair growth treatment.
49 citations,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
19 citations,
December 2021 in “Cureus” Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.
12 citations,
January 2021 in “Drugs in R&D” Isotretinoin is effective for treating dissecting cellulitis, but recurrence is common.
4 citations,
December 2022 in “Frontiers in Bioengineering and Biotechnology” Exosomes show promise for improving wound healing, reducing aging signs, preventing hair loss, and lightening skin but require more research and better production methods.
4 citations,
December 2020 in “Journal of Dermatology” Impaired autophagy may cause hair loss by triggering early catagen.
40 citations,
December 2011 in “British Journal of Dermatology” Women's hair generally gets thinner and less dense starting in their mid-thirties, with hair loss becoming more common as they age due to both genetics and environment.
December 2016 in “Journal of evolution of medical and dental sciences” Skin problems are common in thyroid disorders, with dry skin in hypothyroidism and warm, soft skin in hyperthyroidism.
16 citations,
December 2017 in “Journal of Pediatric and Adolescent Gynecology” Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.
36 citations,
December 2015 in “Drugs” New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.
7 citations,
May 2020 in “Trends in molecular medicine” The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.