research Economic Analysis of Finasteride: A Model-Based Approach Using Data from the Proscar Long-Term Efficacy and Safety Study
Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.
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research Psoriatic Scarring Alopecia: A Case Report
A woman with long-term scalp psoriasis developed rare scarring hair loss that didn't fully respond to treatments.
research Antiandrogenic Therapy with Cyproterone Acetate in Female Patients with Androgenetic Alopecia and Acne Vulgaris
Ciproterone acetate improves hair regrowth and acne in most female patients.
research A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women
Platelet-rich plasma helps hair regrowth and improves quality of life in women with hair loss, but minoxidil may be more effective.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice
Prolactin affects when mice shed and grow hair.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Polycystic Ovary Syndrome and the Risk of Obstructive Sleep Apnea: A Meta-Analysis and Review of the Literature
Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.
research Autoimmune Polyglandular Syndrome Type 1 in Russian Patients: Clinical Variants and Autoimmune Regulator Mutations
Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
research Nanoparticles in Wound Healing: From Hope to Routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research Structural and Dynamic Insights into Substrate Binding and Catalysis of Human Lipocalin Prostaglandin D Synthase
The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
research Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth
Substance from human umbilical cord blood cells promotes hair growth.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.
research Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin
lncRNAs may regulate hair follicle development in Hu sheep.
research Hair Follicles and Their Role in Skin Health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research Effects of Polycystic Ovary Syndrome on Health-Related Quality of Life
PCOS lowers quality of life, causing issues like obesity, infertility, and menstrual problems.
research Current Concepts in Aesthetic Endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice
Prolactin affects when mice shed and grow hair.
research Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.
research The Wound Microbiome
The document concludes that better understanding the wound microbiome can improve chronic wound care by preserving helpful bacteria and targeting harmful ones.
research Hair and Nail Disorders of Childhood
The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Menopause
The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.
research Dermatologic Adverse Events from Cancer Treatments
Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
research The Impact of Obesity on the Folliculosebaceous Unit
Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.
research Case 1: Severe Acne – Not Just Skin Deep
Severe acne in a young girl may indicate underlying hormonal issues.
research MR Imaging of Hair and Scalp for the Evaluation of Androgenetic Alopecia
MRI helps evaluate androgenetic alopecia severity.
research Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth Ex Vivo
Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.
research Role of Annexin A2 Isoform 2 on the Aggregative Growth of Dermal Papillae Cells
Annexin A2 isoform 2 helps dermal papillae cells grow, affecting hair growth.