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- Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
- Alopecia - the search for novel agents continues
- Design and synthesis of novel Azasteroids and Pseudoazulenyl nitrones
- 5α-Reductase Inhibitors, Chemical and Clinical Models
- Novel inhibitors of 5α-reductase
- Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase
- Species Differences in Prostatic Steroid 5<i>α</i>-Reductases of Rat, Dog, and Human
- Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids
- Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases
- In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors
- 12 Treatment of hirsutism with 5α-reductase inhibitors
- 13C-NMR study of 4-azasteroids in solution and solid state
- Evaluation of New Pregnane Derivatives as 5.ALPHA.-Reductase Inhibitor.
- Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride
- A concise review- Development of an analytical method and validation of dutasteride
- Synthesis and Study of Some 17a-aza-D-homo Steroids as 5α-Reductase Inhibitors
- Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
- Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase
- Structural studies of two solid steroid compounds
- New 5?-reductase inhibitors: In vitro and in vivo effects
- Phytochemicals as emerging therapeutic agents for alopecia treatment
- Relative binding affinity of novel steroids to androgen receptors in hamster prostate
- A 5'-upstream region of a bovine keratin 6 gene confers tissue-specific expression and hyperproliferation-related induction in transgenic mice.
- Effect of finasteride in idiopathic hirsutism
- Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche.
- DEVELOPING AND VALIDATING AN HPLC METHOD TO QUANTIFY SIMULTANEOUSLY DUTASTERIDE AND THEIR RELATED MOLECULES (DUTASTERIDE ACID, 2,5 BIS- (TRI FLUORO METHYL)-ANILINE AND DUTASTERIDE 17 α-EPIMER) IN CAPSULES
- Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1
- Biological activity of novel progesterone derivatives having a bulky ester side chains at C-3
- An overview on 5α-reductase inhibitors
- Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2