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Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride is a safe, effective treatment for hirsutism with fewer side effects.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Three Indian medicinal plant compounds help hair growth.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.