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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Androgens can help prevent memory problems caused by apoE4.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Platelet-rich plasma may help in skin and hair treatments, and with muscle and joint healing, but more research is needed to fully understand its benefits and limitations.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

New LPA receptors (LPA4, LPA5, LPA6) have diverse roles in the body.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Certain drugs that block specific enzymes can help treat prostate diseases.

Trichohyalin is also found in the outer layers of normal human skin.