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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Finasteride for female hair loss has low side effects, more research needed.

5ARI treatment improves hair growth in older men with minimal side effects.

Finasteride for hair loss lowers PSA levels, so PSA values need adjusting when screening for prostate cancer.

Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.

Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.

Some common medications can harm male fertility, but many effects can be reversed.

New treatments for male hypogonadism are effective and should be personalized.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Finasteride reduces corpus cavernosum weight but doesn't affect erectile response in rats.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Poor sleep is linked to a higher risk of developing and worsening urinary problems in men.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Dutasteride reduces DHT more effectively than finasteride.

Taking oral isotretinoin with creams worked better for treating a type of hair loss than creams alone.