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    Research 31–60 of 1000+

    1. Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats Frontiers in Pharmacology · 2025 · 2 citations
    2. <i>Melandrium firmum</i>Extract Promotes Hair Growth by Modulating 5α-Reductase Activity and Gene Expression in C57BL/6J Mice Annals of Dermatology · 2019 · 2 citations
    3. Finasteride, a 5alpha-reductase enzyme inhibitor, alone and synergism with a neurosteroid reduces responsiveness to nociceptive stimuli in male rat Journal of Pain · 2009
    4. Bioprospecting of Potential Inhibitors of 5alpha Reductase 2 Inhibitors from Relevant Ethno-pharmacological Plants via In Silico Techniques Scientific African · 2024
    5. [Effect of selective 5alpha-reductase inhibitor or/and testosterone undecanoate on the reproductive function of male rats]. PubMed · 2005
    6. Association of long-term 5α-reductase inhibitor use with survival in men with renal cell carcinoma: a nationwide population-based cohort study Frontiers in Pharmacology · 2026
    7. Identification of xenobiotics interfering with 5 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e152" altimg="si21.svg"> <mml:mi>α</mml:mi> </mml:math> -reductase (SRD5A2) activity Toxicology Letters · 2026
    8. The relevance of using 5α-reductase inhibitors in the conservative management of benign prostatic hyperplasia: A review Consilium Medicum · 2025
    9. Differential association between cumulative dose of 5α-reductase inhibitors and mortality Scientific Reports · 2025
    10. In Vitro Skin Penetration of 5α-Reductase Inhibitors from Tectona grandis L.f. Leaf Extracts Molecules · 2025
    11. Dihydrotestosterone and 5α-Reductase Humana Press eBooks · 2003
    12. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    13. Extract of <i>Plumbago zeylanica</i> enhances the growth of hair follicle dermal papilla cells with down‐regulation of 5α‐reductase type II Journal of Cosmetic Dermatology · 2020 · 4 citations
    14. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    15. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    16. Structure of human type II 5 alpha-reductase gene. Endocrinology · 1992 · 124 citations
    17. 9 Role of 5α-reductase in health and disease Baillière's clinical endocrinology and metabolism · 1994 · 101 citations
    18. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    19. Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase Journal of Medicinal Chemistry · 1993 · 89 citations
    20. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials The Journal of Sexual Medicine · 2016 · 57 citations
    21. Inhibition of 5α-Reductase, IL-6 Secretion, and Oxidation Process of Equisetum debile Roxb. ex Vaucher Extract as Functional Food and Nutraceuticals Ingredients Nutrients · 2017 · 49 citations
    22. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    23. Anabolic effects of testosterone are preserved during inhibition of 5α-reductase 2007 · 42 citations
    24. 7 Regulation of androgen receptor and 5α-reductase in the skin of normal and hirsute women Clinics in endocrinology and metabolism · 1986 · 35 citations
    25. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    26. Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase BJU international · 2009 · 29 citations
    27. Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles Archives of Dermatological Research · 1999 · 28 citations
    28. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    29. Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase Journal of Medicinal Chemistry · 2001 · 27 citations
    30. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations