3 citations,
September 2023 in “International journal of impotence research” Post-finasteride syndrome causes lasting sexual, mental, and physical issues, needing more research for solutions.
20 citations,
January 2004 in “PubMed” April 2021 in “Texila international journal of academic research” The study compared the effectiveness of topical versus systemic finasteride in treating male androgenic alopecia. It involved 30 male patients divided into two groups: one received topical finasteride (0.1%) with minoxidil (5%), and the other received topical minoxidil with oral finasteride (1 mg). Over 6 months, both groups showed significant increases in hair counts and terminal hair counts. Initially, the topical group showed better improvement, but long-term results indicated that both treatments were similarly effective.
33 citations,
March 2016 in “Indian Journal of Dermatology, Venereology and Leprology” Taking 1 mg of finasteride daily can increase hair count and improve hair appearance, but it may have side effects on sexual function and a potential risk of prostate cancer. It may not be effective for postmenopausal women unless taken in higher doses.
31 citations,
January 2001 in “PubMed” 6 citations,
November 2018 in “Journal of molecular histology” Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.
12 citations,
August 2004 in “PubMed” Finasteride, especially in a 1mg dose, effectively slows hair loss and improves hair growth in Japanese men with male pattern hair loss.
4 citations,
June 2022 in “Journal of Infection” Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.
2 citations,
February 2007 in “PubMed” 1 citations,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
14 citations,
May 2016 in “Therapeutic advances in urology” Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.
13 citations,
January 2008 in “Springer eBooks” 3 citations,
October 2021 in “Clinical, Cosmetic and Investigational Dermatology” Setipiprant did not significantly improve hair growth in men with hair loss.
2 citations,
May 2023 in “Experimental neurology” Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.
1 citations,
January 2022 in “Annals of Dermatology” Dutasteride is more effective than finasteride for long-term hair growth in men with androgenic alopecia.
October 2022 in “Biomolecules” Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.
August 2021 in “Asian Journal of Pharmaceutical and Clinical Research” Plant extracts in shampoo improved hair thickness and density in men with hair loss.
20 citations,
January 2002 in “PubMed” Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.
4 citations,
January 2001 in “PubMed” 3 citations,
January 2022 in “Scientific Reports” A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.
2 citations,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
2 citations,
September 2001 in “PubMed” Finasteride is advertised directly to consumers for treating male pattern hair loss.
1 citations,
November 2010 in “Anticancer Research” 1 citations,
April 2022 in “Journal of Cosmetic Dermatology” March 2024 in “Journal of Endocrinological Investigation” Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.
November 2023 in “Frontiers in Neuroendocrinology” Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.
April 2022 in “Authorea (Authorea)” CT scans can find serious prostate cancer even when PSA levels are low.
August 2023 in “International journal of impotence research” Many dermatologists believe finasteride can cause sexual side effects and counsel patients about them.
May 2023 in “Brazilian Journal of Health Review” The study aimed to evaluate the pharmacokinetic profile and bioequivalence of a fixed combination tablet containing finasteride (5 mg) and doxazosin (2 mg) compared to the individual administration of these drugs. Conducted as a randomized, crossover study with 30 subjects, the results showed no significant differences in the pharmacokinetic parameters (AUC0-72h, AUC0-∞, and Cmax) between the combination tablet and the single agents. The mean ratios of AUC0-72h/AUC0-∞ for finasteride and doxazosin were nearly 100%, indicating adequate sampling time and confirming bioequivalence. This suggests that the combination tablet does not alter the pharmacokinetics of the individual drugs, supporting its use in clinical practice.
January 2023 in “Iranian Journal of Pharmaceutical Research”