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The study created a new method to test drugs that affect hormone processing in skin.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Some plant-based products might treat hair loss with fewer side effects than current medications.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.

Dutasteride reduces DHT more effectively than finasteride.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Nanoliposomes loaded with saw palmetto extract could be good for treating hair loss.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Testosterone helps human pancreatic cells increase insulin release.

Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.

Testosterone affects stress hormone levels differently in adolescent and adult male rats.

Ultra-high molecular weight poly-γ-glutamic acid may help promote hair growth.