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Intradermotherapy with minoxidil is as effective as topical application for treating hair loss.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

Certain gene variants may raise the risk of prostate enlargement, but taking NSAIDs could reduce this risk.

Some medications may cause lasting sexual dysfunction.

Early balding in men is linked to metabolic syndrome, so screening is important for prevention.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Knowing about finasteride's sexual side effects increases reported dysfunction.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Hair loss needs more research for better treatments.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Laser device increases hair density, safe for treating hair loss in men and women.

Use minoxidil for hair loss treatment; assess results after 6 months.

The conclusion is that the risk of losing significance in meta-analysis results increases with smaller effects and more missing data, and using the median standard deviation for imputation is recommended.

Finasteride effectively treats baldness but may cause sexual side effects.