Search
for

    Sort by

    Research 121–150 of 1000+

    1. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    2. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016 · 33 citations
    3. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    4. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    5. Long-term use of 5α-reductase inhibitors and the risk of male breast cancer Cancer Causes & Control · 2014 · 28 citations
    6. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation Neuropsychopharmacology · 2017 · 27 citations
    7. 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction Neurobiology of Disease · 2018 · 26 citations
    8. 5alpha-reductase 2 inhibition impairs brain defeminization of male rats: Reproductive aspects Pharmacology Biochemistry and Behavior · 2005 · 26 citations
    9. In vivo evidence for an increase in 5alpha‐reductase activity in the rat central nervous system following morphine exposure International Journal of Developmental Neuroscience · 2005 · 25 citations
    10. Cloning, expression and characterization of rhesus macaque types 1 and 2 5alpha-Reductase: evidence for mechanism-Based inhibition by finasteride The Journal of Steroid Biochemistry and Molecular Biology · 1998 · 25 citations
    11. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    12. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    13. Persistent Erectile Dysfunction after Discontinuation of 5-Alpha Reductase Inhibitor Therapy in Rats Depending on the Duration of Treatment The World Journal of Men s Health · 2018 · 17 citations
    14. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    15. 5alpha-reductase inhibitors - a new hope in dermatology? International Journal of Dermatology · 1997 · 15 citations
    16. 5-Alpha-Reductase Inhibitors and Combination Therapy Urologic Clinics of North America · 2016 · 15 citations
    17. Sexual Dysfunction Related to Drugs: a Critical Review. Part V: α-Blocker and 5-ARI Drugs Pharmacopsychiatry · 2015 · 15 citations
    18. Role of 5 alpha-reductase inhibitors in the management of prostate cancer Clinical interventions in aging · 2006 · 15 citations
    19. Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline Journal of Clinical Periodontology · 1998 · 15 citations
    20. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021 · 14 citations
    21. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations
    22. Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats Pharmacology Biochemistry and Behavior · 2010 · 13 citations
    23. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    24. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
    25. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    26. Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach Plants · 2024 · 12 citations
    27. Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals European Journal of Drug Metabolism and Pharmacokinetics · 2008 · 11 citations
    28. Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment Journal of Chemistry · 2023 · 10 citations
    29. Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment F1000Research · 2021 · 8 citations
    30. An update on the use of 5alpha-reductase inhibitors Drugs of today · 2004 · 7 citations