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Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Finasteride harms Daphnia magna's reproduction, growth, and metabolism.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Androgens can both increase and decrease hair growth in different parts of the body.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride can cause sexual problems and depression in young men.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Finasteride helps hair growth but may cause sexual side effects and depression.

Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Women with hair loss had higher levels of certain hormones, suggesting a link to a condition like PCOS.