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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Finasteride boosts morphine's pain relief, stops tolerance, and reduces withdrawal in rats.

Finasteride helps protect brain in old male rats.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride doesn't affect sleep spindles in men.

Dutasteride may help shrink prostate cancer tumors.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Some herbs show promise as antiandrogenic agents.

Rats had lasting erectile problems after stopping a certain medication.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Dutasteride works better than finasteride for hair loss, with both being safe to use.