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Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Topical 5α-reductase inhibitor helps counteract hair loss and stabilize it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

Both drugs lower DHT levels, with GI198745 being more effective.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Lygodii Spora extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

Minoxidil boosts enzymes that help hair growth.

Finasteride and minoxidil together promote hair growth better than either alone.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Finasteride helps reduce pain and inflammation in animals.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.