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Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride potentially treats hair loss by reducing DHT production.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride doesn't affect erections much, but may decrease libido in men.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

Compounds from the plant Mammea siamensis may help treat hair loss.

Certain drugs change freshwater snail shells to a "banana" shape.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Glioblastoma cells can make androgens, which might help the tumor grow.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Ganoderma lucidum may help treat enlarged prostate in rats.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Testosterone helps human pancreatic cells increase insulin release.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Male pattern baldness involves genetics, hormones, and needs better treatments.