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Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

Finasteride reduces movement issues in Parkinson's disease rats.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride exposure harms tadpole reproduction and hormone balance.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Tamsulosin increases the risk of floppy iris during eye surgery.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Finasteride doesn't affect erections much, but may decrease libido in men.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

The review suggests there's no agreed treatment for Frontal Fibrosing Alopecia, but hydroxychloroquine and 5a-reductase inhibitors are most effective. New treatments like platelet-rich plasma and LED light could help if standard treatments fail.

The higher dose supplement was more effective in treating female hair loss.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Dutasteride is more efficient than finasteride, but individual results vary.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride doesn't harm bone density in older men with BPH.