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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Glioblastoma cells can make androgens, which might help the tumor grow.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Licorice extract helps hair growth and may treat hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.

Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Late pregnancy helps repair brain damage in rats due to the GABAergic system.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

The nutritional supplement improved hair quality and reduced hair loss.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

Applying an extract from Perilla frutescens helps hair grow and fights the effects of hair loss hormones.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Hair loss may increase heart disease risk.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.