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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride improves hair growth in men with androgenetic alopecia.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Some common medications can harm male fertility, but many effects can be reversed.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Plant extracts may help treat hormone-related hair loss.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

A new compound effectively inhibits human 5α-reductase 1.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.