39 citations,
April 2018 in “Hormones” No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
30 citations,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
18 citations,
June 2009 in “Journal of Molecular Endocrinology” Finasteride exposure harms tadpole reproduction and hormone balance.
46 citations,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
21 citations,
January 2003 in “Skin pharmacology and physiology” Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.
97 citations,
April 2016 in “Andrology” Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.
39 citations,
September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
21 citations,
February 2017 in “International Journal of Women's Dermatology” Hormonal therapies help treat female hair loss, but results are slow and vary.
1 citations,
November 2008 Yonnyuniksoogobon-dan taken orally promotes hair growth by affecting growth factors in hair roots.
6 citations,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
January 2014 in “Springer eBooks” Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
January 2024 in “Journal of Biosciences and Medicines” Future treatments for androgenic alopecia may focus on reactivating hair follicle stem cells and improving drug delivery.
1 citations,
October 2010 in “Cambridge University Press eBooks” Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
27 citations,
July 2012 in “Dermatologic Surgery” Higher caspase-1 levels found in balding scalps; reducing it may help treat hair loss.
17 citations,
June 2012 in “Australasian Journal of Dermatology” Finasteride and low-dose dutasteride combo improves hair growth and reduces hair loss with no major side effects.
8 citations,
April 2016 in “Anais Brasileiros De Dermatologia” Right hand finger ratio may predict male hair loss.
48 citations,
January 2017 in “Skin Pharmacology and Physiology” Finasteride-loaded nanoparticles may help treat alopecia.
24 citations,
November 2009 in “Pharmaceutical Development and Technology” Transcutol P best increases Finasteride absorption for hair loss treatment.
18 citations,
August 2019 in “Drug Development and Industrial Pharmacy” Quercetin-loaded nanoparticles can penetrate skin, minimize hair loss, and promote hair regrowth, showing slightly better results than a marketed product.
18 citations,
July 2009 in “Drug Metabolism and Disposition” Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.
13 citations,
January 2015 in “Toxicology Letters” Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
10 citations,
June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
8 citations,
February 2017 in “Clinical Drug Investigation” Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.
5 citations,
January 2020 in “Skin appendage disorders” Oral dutasteride works better for hair loss, but has more sexual side effects; intralesional dutasteride is a possible alternative.
3 citations,
July 2019 in “Experimental Dermatology” Hair loss patients may have different polyamine levels in various scalp areas.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
39 citations,
December 2013 in “Phytotherapy Research” Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.
19 citations,
January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
12 citations,
July 2020 in “International Journal of Pharmaceutics” Iron oxide nanoparticles improve skin penetration and drug release for hair loss treatment.
4 citations,
July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.