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    Research 61–90 of 1000+

    1. Natural Product-Inspired Bis(trifluoromethyl) Phenyl Hydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitors of Human Steroid 5α-Reductase Type-1: Synthesis, <i>In Vitro</i>, and <i>In Silico</i> Studies ACS Omega · 2025
    2. Association of 5-α reductase inhibitors and sexual dysfunction: A RADAR report Journal of The American Academy of Dermatology · 2013
    3. 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy European Urology Supplements · 2016
    4. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    5. 5-Alpha-Reductase Inhibitors and Combination Therapy Urologic Clinics of North America · 2016 · 15 citations
    6. 5-Alpha-reductase deficiency in a Saudi "girl" Postgraduate medical journal · 1995 · 1 citations
    7. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    8. HPLC Profiling and Insilco studies of Chochurus olitoris (Jute) Leave Fractions against Steroid 5α-Reductase 2 (SRD5α2) Biomedical Journal of Scientific & Technical Research · 2024
    9. Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men Advances in Experimental Medicine and Biology · 2017 · 31 citations
    10. In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996 · 29 citations
    11. Concomitant immobilization of androgen receptors and 5α- reductase in androgenic alopecia International Journal of Dermatology Research · 2025
    12. The Benefits of Dual Inhibition of 5α Reductase European Urology Supplements · 2006 · 4 citations
    13. Avicequinone C Isolated from Avicennia marina Exhibits 5α-Reductase-Type 1 Inhibitory Activity Using an Androgenic Alopecia Relevant Cell-Based Assay System Molecules · 2014 · 19 citations
    14. A New Look at the 5á-Reductase Inhibitor Finasteride 2006
    15. Inhibitory Effects of Pueraria mirifica Aqueous Extracts on 5α-reductase and Prostate Histomorphometry in Testosterone-induced Benign Prostatic Hyperplasia Sprague Dawley Rats 2023
    16. Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates The Journal of Steroid Biochemistry and Molecular Biology · 1995 · 13 citations
    17. 705 Influence of 5a-Reductase Inhibitor (5-ARI) Usage on the Reproductive Function of Married Men The Journal of Sexual Medicine · 2018
    18. Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors Assay and Drug Development Technologies · 2018 · 11 citations
    19. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    20. Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients European Urology Supplements · 2003 · 12 citations
    21. Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells Applied Biological Chemistry · 2026
    22. Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells 2023
    23. Effects of Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose on androgenic alopecia via inhibiting 5a-reductase and regulating Wnt/β-catenin pathway Fitoterapia · 2024
    24. In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands Current Enzyme Inhibition · 2020
    25. 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives International Journal of Biological Macromolecules · 2011 · 26 citations
    26. 5α-Reductase Inhibitory Components as Antiandrogens From Herbal Medicine Journal of acupuncture and meridian studies · 2010 · 19 citations
    27. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    28. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    29. Treatment of male rats with finasteride, an inhibitor of 5alpha-reductase enzyme, induces long-lasting effects on depressive-like behavior, hippocampal neurogenesis, neuroinflammation and gut microbiota composition Psychoneuroendocrinology · 2018 · 37 citations
    30. 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish Communications Biology · 2026