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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Dutasteride is more efficient than finasteride, but individual results vary.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

New tests detect finasteride and dutasteride in urine quickly and easily.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

Treatment for benign prostatic hyperplasia involves drugs that either quickly relieve symptoms or reduce prostate size, with a combination offering more benefits but more side effects.

Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.

Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Hair loss lotion with specific ingredients effectively improves hair growth and thickness safely.