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The study created a new method to test drugs that affect hormone processing in skin.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

Finasteride helps hair regrowth in frontal fibrosing alopecia.

Personalized treatment with inhibitors, minoxidil, and laser therapy helps hair loss.

Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.

Finasteride's effectiveness for frontal fibrosing alopecia is uncertain.

Finasteride reduces hair growth in women with hirsutism and works better with electrolysis.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.

Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.

Long-term finasteride use doesn't change bone density or metabolism.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Certain drugs change freshwater snail shells to a "banana" shape.

5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.

Finasteride effectively treats BPH, but needs more trials to understand potential.