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Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.

Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

A natural steroid in the body may protect against eye damage in glaucoma.

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.