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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Hair loss requires customized treatments based on its various causes and types.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Combining laser hair removal with topical eflornithine is recommended for better results in treating unwanted facial hair.

Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Mutations in certain receptors can cause diseases and offer new treatment options.

Finasteride can cause sexual problems and depression in young men.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.

Azelaic Acid is effective and safe for treating adult female acne, with few side effects.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

The document concludes that proper diagnosis and evidence-based treatments are crucial for managing hair diseases, and psychological support for patients is important.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

Some conditions mimic PCOS symptoms and need careful diagnosis to treat potentially serious health issues.